Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. The increased evidence obtained from cultured cells or animal experiments reveal a putative place for H₂ treatment and its radioprotective effect clinically. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Recently, the pathophysiological effects of inhaled gases including nitric oxide (NO), molecular hydrogen (H₂), and xenon (Xe) have attracted much…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Recent studies have reported that ROS activate NLRP3 inflammasomes, and that this stimulation triggers the production of proinflammatory cytokines. The…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Safety of both Xe and H₂ after cardiac arrest has been reported in phase 1 clinical trials. The reviewed evidence…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen (H₂) and formate (HCOO-) are metabolic end products of many primary fermenters in the mammalian gut. The reviewed…
Read ArticleIn participants, molecular hydrogen (H₂) inhalation had beneficial health effects in terms of improved physical (6-min walking test) and respiratory function in patients with post-COVID-19. These findings add…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The growing global epidemic of obesity and type 2 diabetes mellitus has determined an increased prevalence of NAFLD (non-alcoholic fatty…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Important metabolic variables that lead to the development of many diseases, including "mitochondrial diseases," include increased oxidative stress and mitochondrial…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ is capable of capturing harmful •OH and ONOO- while maintaining the crucial reactive oxygen species (ROS) involved in cellular…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. However, limitations include hydrogen termination upon material depletion and reduced bioavailability at targeted lesions. The reviewed evidence adds support for…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Direct delivery of hydrogen gas and HRW to the respiratory and digestive systems can enhance the bioavailability of H₂ at…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Many clinical trials are constrained by small sample sizes and limited patient diversity, with aged and female patients frequently under-represented,…
Read ArticleThis narrative review examined the therapeutic potential of H₂ in preventing and treating sensorineural hearing loss and aims to inform future research directions. After 4 weeks of H₂…
Read ArticleThis systematic review examined this study aims to systematically investigate current evidence from animal experiments and the effects of administration preconditions in acute and late phases after CO…
Read ArticleThis narrative review examined to synthesize experimental and clinical evidence on mitochondria-targeted strategies in acute pancreatitis (AP) and evaluate the potential of interventions that preserve or restore mitochondrial…
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