Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients.

This narrative review proposes that molecular hydrogen's antioxidant and anti-inflammatory actions might help limit cytokine storm, lung injury, and severe disease in COVID-19, but it does not report a new clinical trial. The authors explicitly state that efficacy and safety require large clinical trials and further confirmation.

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Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology?

This narrative review summarizes preclinical evidence that H₂ inhalation suppressed glioblastoma growth and extended survival in mice, while hydrogen treatment reduced sphere formation, migration, invasion, and colony formation in glioma cells. It also discusses proton-beam therapy as a separate treatment modality. The article does not report a new human clinical trial, so the clinical effectiveness of H₂ for glioblastoma remains unestablished.

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Effects of Alkaline-Reduced Water on Gastrointestinal Diseases

Living a healthy lifestyle is the most important need in the world today. However, oxidative stress (OS) is caused by several stress-inducing factors such as smoking, alcohol consumption, chronic diseases, and inflammatory responses, oxygen-free radicals are produced in excess and can damage major organs in the body. This phenomenon has been implicated in the pathogenesis of several gastrointestinal (GI) diseases, including gastritis, constipation, and inflammatory bowel diseases, which include Crohn’s disease, ulcerative colitis, functional dyspepsia, acid reflux, diverticular disease, and irritable bowel syndrome.

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The role of IL-6 on apical periodontitis: a systematic review.

Effects of hydrogen rich water and pure water on periodontal inflammatory factor level, oxidative stress level and oral flora: a systematic review and meta-analysis - Bai - Annals of Translational Medicine is classified as Meta-analysis using Review or synthesis. The primary model is Published literature review. Detailed outcomes require source review because an abstract was not accessible.

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Hydrogen applications: advances in the field of medical therapy.

Hydrogen (H2) has been widely used in the chemical industry as a reducing agent. As the researches move along, increasing attention has been paid to its biological functions. The selective antioxidant effect of hydrogen is considered to be the main reason for medical applications.

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Review and prospect of the biomedical effects of hydrogen.

Hydrogen, the simplest gas in nature, was recently reported as a therapeutic antioxidant through selectively reducing cytotoxic oxygen radicals. Though hundreds of studies on curative effects of hydrogen were published and justified, the mechanism remains unclear. We proposed several promising directions in this area by relatively in-depth analysis.

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An Overview of SARS-CoV-2 (COVID-19) Infection and the Importance of Molecular Hydrogen as an Adjunctive Therapy

An Overview of SARS-CoV-2 (COVID-19) Infection: The Importance of Molecular Hydrogen as an Adjunctive Therapy | Reactive Oxygen Species is classified as Narrative review using Review or synthesis. The primary model is Published literature review. Detailed outcomes require source review because an abstract was not accessible.

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A critical review for hydrogen application in agriculture: Recent advances and perspectives

With the climate change and urbanization, the area of cultivated land is decreasing, and crops are also subjected to various biological and abiotic stresses. How to improve crop yield and stress resistance has become an urgent agricultural production problem that must be solved. Hydrogen has the characteristics of being green and clean, which has great advantages and is significant for the development of modern agriculture and sustainable agriculture.

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Translational Research of Peritoneal Dialysis Solution With Dissolved Molecular Hydrogen

Translational Research of Peritoneal Dialysis Solution with Dissolved Molecular Hydrogen - Abstract - Recent Advances in Dialysis Therapy in Japan - Karger Publishers is classified as Narrative review using Review or synthesis. The primary model is Published literature review. Detailed outcomes require source review because an abstract was not accessible.

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Recent advances in hydrogen-rich water (HRW): Preparation technologies, functional properties, and applications in the food industry

Recent advances in hydrogen-rich water (HRW): Preparation technologies, functional properties, and applications in the food industry is classified as Narrative review using Review or synthesis. The primary model is Published literature review. Detailed outcomes require source review because an abstract was not accessible.

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[Hydrogen and oxidative stress injury–from an inert gas to a medical gas].

This narrative review examined [Hydrogen and oxidative stress injury--from an inert gas to a medical gas]. The abstract describes Published literature review. The abstract reports: As a result, it could protect tissues against oxidative stress injuries, such as ischemia/reperfusion injury of the heart, liver and intestine, cisplatin nephrotoxicity, sepsis…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen therapy in respiratory diseases: mechanisms, evidence, and technical considerations hydrogen therapy in respiratory diseases

Molecular hydrogen (H₂) has emerged as a promising therapeutic gas in respiratory medicine due to its antioxidative, anti-inflammatory, anti-apoptotic, and immunomodulatory effects. With the rising prevalence of acute and chronic respiratory diseases, H₂ offers potential as a novel adjunctive therapy. This review integrates mechanistic insights, preclinical findings, clinical data, and technical considerations.

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Recent advances in hydrogen research as a therapeutic medical gas.

Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. This review summarizes currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a therapeutic medical gas in diverse models of disease and discusses the feasibility of hydrogen as…

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The potential utilizations of hydrogen as a promising therapeutic strategy against ocular diseases.

This narrative review examined The potential utilizations of hydrogen as a promising therapeutic strategy against ocular diseases. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation therapy for inflammation and eye diseases: a review of the literature.

Hydrogen inhalation therapy for inflammation and eye diseases: a review of the literature is classified as Narrative review using Review or synthesis. The primary model is Published literature review. Detailed outcomes require source review because an abstract was not accessible.

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