Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.
This animal study examined Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice. The abstract describes Mouse model; reported duration 28 days. The abstract reports: ERW exhibits potent nephroprotective effects on cisplatin-induced kidney damage in mice, likely due to both the increase in antioxidant-defense system activity and the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota.
This animal study examined Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota. The abstract describes Mouse model. The abstract reports: In the present study, we found that oral gavage with hydrogen-water increased the survival rate and body weight of mice exposed to total abdominal…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig.
This animal study examined Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far been modest. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells.
This in vitro or cellular study examined Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells. The abstract describes PC12 cell model. The abstract reports: The data showed that H2 promoted the cell viability and inhibited the damage in the cell and mitochondria membrane, reduced the levels of lipid…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.
This uncontrolled human study examined Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 40 min. The abstract reports: This observation demonstrated that hydrogen-rich saline peritoneal injection improves histologic and functional assessment in a rat model of CO encephalopathy. Hydrogen saline has potentials…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles.
This in vitro or cellular study examined The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles. The abstract describes PC12 cell model. The abstract reports: We previously showed that ERW was capable of extending lifespan of Caenorhabditis elegans by scavenging ROS [2]. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats
This animal study examined Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease.
This uncontrolled human study examined Nanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease. The abstract describes Human participants. The abstract reports: Moreover, hepatic transcriptome showed a reprogramed liver metabolism profile with reduced lipid synthesis and increased fatty acid metabolism. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.
This in vitro or cellular study examined Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing the intracellular acetaldehyde, a toxic substance produced by ethanol degradation, in hepatocyte…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis.
This animal study examined Hydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis. The abstract describes Mouse model. The abstract reports: Our results showed that intraperitoneal injection of H improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.
This animal study examined Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 days. The abstract reports: Our findings suggested reduced oxygen utility, mainly in the cortex, in gentamicin-induced nephrotoxicity and an ameliorative effect of hydrogen-rich water against GIN. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.
This animal study examined Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: We found that CsA increased the levels of reactive oxygen species (ROS) and malonaldehyde (MDA), but it reduced glutathione (GSH) and superoxide dismutase (SOD)…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
This animal study examined Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Treatment with HRW resulted in a significant increase in the 5-d survival rate compared with the APAP + NS treatment group (60% vs 26.67%,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo.
This animal study examined Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Results showed that intragastric administration of HRW effectively promoted the elimination of urinary tritium, decreased the level of serum tritium and tissue-bound tritium (OBT),…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.
This animal study examined Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Nissl staining and electron microscopy results indicated that HRW intake had protective effects on the CPF-induced damage of hippocampal neurons and neuronal mitochondria. This is an automated editorial draft based on the abstract and requires source review before publication.
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