Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
This uncontrolled human study examined Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: The present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen resuscitation, a new cytoprotective approach.
This narrative review examined Hydrogen resuscitation, a new cytoprotective approach. The abstract describes Published literature review. The abstract reports: In mammals, endogenous hydrogen is produced as a result of the fermentation of non-digestible carbohydrates by intestinal bacteria and it is absorbed into the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of three hydrogen-rich liquids on hemorrhagic shock in rats.
This animal study examined Effects of three hydrogen-rich liquids on hemorrhagic shock in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Each hydrogen-rich liquid resuscitation preparation could protect the lung against acute injury secondary to UHS. These mechanisms may be associated with hydrogen inhibiting the release of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
This animal study examined Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 3 days. The abstract reports: These results indicate the therapeutic potential of HW in preventing acute injury of the liver with attenuation of an increase in oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury.
This animal study examined Hyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HHOS has protective effects against liver injury in a rat model of HSR. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
This animal study examined Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We have demonstrated that hydrogen gas (H), a selective antioxidant, exerts protective effects in septic mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAerosol inhalation of a hydrogen-rich solution restored septic renal function.
This animal study examined Aerosol inhalation of a hydrogen-rich solution restored septic renal function. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation.
This animal study examined Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation inhibits progression to the “irreversible” stage of shock after severe hemorrhage in rats.
This uncontrolled human study examined Hydrogen gas inhalation inhibits progression to the “irreversible” stage of shock after severe hemorrhage in rats. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThree hydrogen-rich solutions protect against intestinal injury in uncontrolled hemorrhagic shock.
This uncontrolled human study examined Three hydrogen-rich solutions protect against intestinal injury in uncontrolled hemorrhagic shock. The abstract describes Human participants. The abstract reports: Evidence showed that hydrogen inhibited inflammation and reduced oxidative damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
This animal study examined Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings may contribute to clarifying the mechanism of action of H therapy in sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.
This uncontrolled human study examined Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice. The abstract describes Human participants. The abstract reports: We found that 2% H inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway
This animal study examined Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway. The abstract describes Mouse model. The abstract reports: We found that H can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
This animal study examined Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation. The abstract describes Mouse model. The abstract reports: The protective effect of H on cognitive dysfunction induced by SAE may be achieved by inhibiting tau phosphorylation, which is perhaps related with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model
This animal study examined Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…. This is an automated editorial draft based on the abstract and requires source review before publication.
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