Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
This uncontrolled human study examined Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. The abstract describes Human participants. The abstract reports: Recently, it has been suggested that molecular hydrogen (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radicals (*OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine.
This narrative review examined A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and hydrogen bath and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping.
This uncontrolled human study examined Molecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Although the patient ultimately succumbed to irreversible chronic comorbidities on day 86, this case of severe tricuspid regurgitation and Child-Pugh class B alcoholic cirrhosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
This uncontrolled human study examined Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreiTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: A total of 199 differential proteins were related with H in the intestinal protection of sepsis. H-related differential proteins were notably enriched in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRecent Advances in Studies of Molecular Hydrogen against Sepsis.
This narrative review examined Recent Advances in Studies of Molecular Hydrogen against Sepsis. The abstract describes Published literature review. The abstract reports: Molecular hydrogen is a new type of antioxidant with strong free radical scavenging ability, which has been demonstrated to be effective for treating various…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePromising novel therapy with hydrogen gas for emergency and critical care medicine.
This narrative review examined Promising novel therapy with hydrogen gas for emergency and critical care medicine. The abstract describes Published literature review. The abstract reports: Studies undertaken by the Center have suggested possible therapeutic effects of hydrogen gas in relation to various aspects of emergency and critical care medicine,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics.
This animal study examined High-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of high concentration (67%) of H in septic mice improved the survival rate and reduced neuronal injury. Its mechanism might be mediated by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFeasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
This uncontrolled human study examined Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study. The abstract describes Human participants; sample size 107; hydrogen delivered as hydrogen inhalation. The abstract reports: HI in combination with TTM is a feasible therapy for patients with PCAS. (Circ J 2016; 80: 1870-1873). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
This uncontrolled human study examined Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. The abstract describes Human participants. The abstract reports: The results indicated that 2% H gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation.
This animal study examined Hydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 2% hydrogen gas after HSR minimized the extent of lung injury by decreasing MPO activity and reducing infiltration of inflammatory cells into…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs.
This uncontrolled human study examined Effects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
This animal study examined Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. The abstract describes Rat model; sample size 15; hydrogen delivered as hydrogen inhalation. The abstract reports: Combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAPOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
This animal study examined APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis. The abstract describes Mouse model. The abstract reports: Animal experiments helped validate these results. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices.
This uncontrolled human study examined A case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices. The abstract describes Human participants. The abstract reports: Arterial blood gas analysis showed no deterioration, and computed tomography revealed no worsening of pulmonary findings or oxygen demand. This is an automated editorial draft based on the abstract and requires source review before publication.
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