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Fructooligosaccharide feeding during gestation to pregnant mice provided excessive folic acid decreases maternal and female fetal oxidative stress by increasing intestinal microbe-derived hydrogen gas.

By H2HUBB Aug 5, 2026 0 Comments

In mice, hydrogen gas concentrations in maternal livers and whole fetuses in EFA-FOS were significantly higher than those in CONT and EFA, respectively (P <.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…

Hydrogen gas distribution in organs after inhalation: Real-time monitoring of tissue hydrogen concentration in rat.

By H2HUBB Aug 5, 2026 0 Comments

In rats, although animal and clinical studies have reported promising results, hydrogen distribution in organs after administration remains unclear. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…

The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.

By H2HUBB Aug 5, 2026 0 Comments

In rats, however, the reduction of the expression of 8-OHdG, the decrease in the neuronal injury in the hippocampal CA1 sector, and the attenuation in brain water content…

Molecular hydrogen downregulates acute exhaustive exercise-induced skeletal muscle damage.

By H2HUBB Aug 5, 2026 0 Comments

In rats, exercise increased cleaved caspase-3 expression, and H₂ reduced this response. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…

Colloidal platinum in hydrogen-rich water exhibits radical-scavenging activity and improves blood fluidity.

By H2HUBB Aug 5, 2026 0 Comments

When applied with the 0.25-0.5 ppm Pt/PVP-colloid in RW or HW, the level of DPPH radicals decreased to 77.5-59.6% or 16.1-5.6%, in contrast to the level as high…

Molecular Hydrogen Reduces the Degree of Endothelial Alteration under Conditions of Chronic Heart Failure.

By H2HUBB Aug 5, 2026 0 Comments

In a laboratory model, molecular hydrogen inhalations in both regimens caused a decrease in the number of circulating endothelial cells; the most pronounced effect was observed after repeated…

Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice.

By H2HUBB Aug 5, 2026 0 Comments

In mice, intermittent hypoxia significantly increased plasma levels of low- and very low-density cholesterol and the amount of 4-hydroxy-2-nonenal-modified protein adducts in the LV myocardium. These preclinical findings…

Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology?

By H2HUBB Aug 5, 2026 0 Comments

In The sphere-forming ability of glioma cells was suppressed by hydrogen treatment, the sphere-forming ability of glioma cells was suppressed by hydrogen treatment. The authors concluded that experimental…

Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation.

By H2HUBB Aug 5, 2026 0 Comments

In male Wistar rats, during mild SI, H₂ reduced plasma surges of proinflammatory cytokines (TNF-α and IL-6) while caused an increase in plasma IL-10 (anti-inflammatory cytokine) and prevented…

Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis.

By H2HUBB Aug 5, 2026 0 Comments

In mice, HRW-treated mice exhibit improved serum lipid profiles, including decreased levels of low-density lipoprotein (LDL), triglycerides (TG), and total cholesterol (T-CHO), as well as reduced lipid accumulation.…

Neuroprotective Effects of Molecular Hydrogen via Oxidative Stress and Neuroinflammation Regulation in a 5xFAD Mouse Model.

By H2HUBB Aug 5, 2026 0 Comments

In the hippocampus, H₂ upregulated nuclear factor erythroid 2-related factor 2 (NRF2), attenuated nuclear factor kappa B (NF-κB) activation, reduced the BAX/BCL-2 ratio, preserved neuronal nuclei (NEUN) expression,…

Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen.

By H2HUBB Aug 5, 2026 0 Comments

The researchers found that administering a persistent H₂-generating supplement increased the human exhaled H₂ concentration (p < 0.01) and improved tear stability (p < 0.01) and dry eye…

Effect of CO2 and H2 gas mixture in cold water immersion on recovery after eccentric loading.

By H2HUBB Jul 30, 2026 0 Comments

In 34 healthy participants, CO₂/H₂ cold-water immersion helped preserve isometric strength, countermovement-jump height, and range of motion after eccentric exercise compared with the other recovery conditions. Muscle soreness…

Hydrogen as a Potential Therapeutic in Obesity: Targeting the Brain.

By H2HUBB Jul 28, 2026 0 Comments

This publication examined molecular hydrogen using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…

Successful treatment of encapsulating peritoneal sclerosis by hemodialysis and peritoneal lavage using dialysate containing dissolved hydrogen.

By H2HUBB Jul 28, 2026 0 Comments

H2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Molecular hydrogen dialysis study…