Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This animal study examined Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress. The abstract describes Rat model; sample size 84; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration…
Read ArticleIn a laboratory model, hS treatment mitigated isoflurane-induced ROS accumulation, opening of mitochondrial permeability transition pores, reduction in mitochondrial membrane potential, and reduction in cellular ATP levels. The…
Read ArticleIn mice, hydrogen-rich water improved brain energy metabolism disorders and intestinal flora imbalances and reduced inflammatory reactions. These results are preclinical and suggest molecular hydrogen's therapeutic potential in…
Read ArticleIn a laboratory model, taken together, the findings suggest that HRW may have potential therapeutic value to inhibit Aβ-induced neurotoxicity. These findings from a laboratory model add evidence…
Read ArticleThe researchers found that hydrogen-rich water significantly improved cognitive behaviour in female transgenic AD mice without affecting Aβ clearance, and reversed the brain oestrogen level, ERβ, and brain-derived…
Read ArticleIn an animal model, HRW reduced the number of harmful bacteria linked to AD pathology by restoring the balance of microbiota in the gut. These preclinical findings add…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. This review provides a comprehensively overview of the therapeutic potential of hydrogen in AD. The reviewed evidence adds support for…
Read ArticleThis human publication evaluated hydrogen gas in 8 patients with AD. This open-label, pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the…
Read ArticleIn 40 participants, a significant treatment vs. time interaction was found for telomere length (P = 0.049), with the length increased after HRW intervention (from 0.99 ± 0.15…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn Decreased Ca2+ signaling is observed in aged cells, probably secondary to the formation of disulfide bonds among Ca2+ signaling-related proteins,, skin aging processes may involve ROS-induced protein…
Read ArticleIn mice, H₂ improved aging-related biomarkers, ie, total antioxidant capacity, advanced glycation end products, tumor necrosis factor-α, free fatty acids, and alanine aminotransferase in plasma. These preclinical findings…
Read ArticleIn H₂ produced by gut bacteria diffuses throughout the body to scavenge cyto •OH in cells, further, H₂ suppressed increased H₂O₂ by suppressing cyto •OH-mediated lipid peroxide formation…
Read ArticleIn The accumulation of β-galactosidase in the cytoplasm and the appearance of abnormal nuclei were inhibited by daily treatment of cells with hydrogen water, thus, this study showed…
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