Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, it was found that systemic HRW treatment slightly suppressed autophagy and then activated the Keap1-Nrf2 signaling pathway by maintaining the Keap1-Nrf2-P62 interaction and improved the osteoporotic fracture healing process. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Studies have shown that H₂ inhalation for about 2 weeks can restore the body’s redox balance and enhance immune cells’…
Read ArticleIn rats, the edema area in TBI+HW group was slightly smaller than that of TBI group, and the surrounding edema was slightly reduced. These preclinical findings add evidence…
Read ArticleIn rats, the mRNA and protein expressions of AQP1 in cerebral cortex were significantly decreased after hydrogen-rich water treatment [24-hour AQP1 mRNA (2-△△Ct):5.40±0.21 vs.7.50±0.26, 24-hour AQP1 protein (gray…
Read ArticleIn rats, compared with the model group, the inflammatory response of pregnancy gingivitis in HW group was significantly suppressed along with decreased NFκB and TNF-α. These preclinical findings…
Read ArticleThis narrative review examined the research progress of hydrogen-rich water for eye diseases in the domestic and foreign literatures. (Chin J Ophthalmol, 2018, 54: 631-635). At present, there…
Read ArticleIn rats, nSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, hydrogen rich water can up-regulate the expression of Nrf2, and reduce oxidative damage of traumatic brain injury in rats. These preclinical findings add evidence supporting molecular…
Read ArticleIn an animal model, kRAS, YWHAE, SP1 and MSRA might be regarded as focused biomarkers to assess the prognosis of EC. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, the daily administration of HRW also progressively reduced the thermal allodynia induced by PTX injection ( p < 0.001; one-way ANOVA, against vehicle plus vehicle-treated animals;…
Read ArticleIn a laboratory model, with the increase of hydrogen-rich water pretreatment concentration, and the duration of action, the cell survival rate increased first and then decreased. These findings…
Read ArticleIn rats, after the HRW treatment, the oxidative stress status in the liver was improved, SOD activities and MDA levels were restored, CAT activities and GSH levels were…
Read ArticleIn an animal model, compared with the MC group, both HRW and LAC treatments attenuated the reduction of villus height in small intestines (duodenum, jejunum, and ileum) caused…
Read ArticleThis publication examined hydrogen-rich water using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Of these studies, eleven studies reported the clinical findings associated with oral ingestion of liquid HRW and three studies identified…
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