Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In The researchers validate its protective effects (1) in vitro with cardiomyocytes and keratinocytes, (2) ex vivo in I/R hearts and (3) in vivo in skin I/R pressure ulcers, molecular hydrogen (H₂) protects organs from reactive oxygen species damage associated with ischemia-reperfusion…
Read ArticleIn a laboratory model, a pronounced decrease—by approximately 2.5 G -units—in G ( • OH) is observed in the 1–100 μs time range in the presence of added…
Read ArticleIn female Sprague-Dawley rats, combination therapy with H₂ and minocycline significantly outperformed H₂ monotherapy in both neurological recovery and infarct reduction, with no sex differences observed. These preclinical…
Read ArticleIn male C57BL/6 mice, each treatment reduced pain-like behaviors in a dose-dependent manner, while co-administration of HRW with JWH-133 or pregabalin produced greater analgesic effects. These preclinical findings…
Read ArticleIn an animal model, based on these results, the researchers can conclude that H₂ administration through both routes mitigated heart damage caused by irradiation after 2 and 9…
Read ArticleIn rats, instead, HRW specifically attenuated the local senescent microenvironment, with a reduction in both SA-β-gal activity and the expression of p16, p21 within the fracture gap. These…
Read ArticleIn an animal model, hydrogen-rich water intake inhibited an increase in serum ROS level and lowered expression of 8-hydroxydeoxyguanosine and nitrotyrosine in the periodontal tissue at 4 weeks.…
Read ArticleIn mice, this study proved that prophylactic treatment with DULO combined with HRW prevented the mechanical allodynia and muscle strength deficits caused by CIS in mice of both…
Read ArticleIn rats, bOLD MRI may be useful for demonstrating the change in R2 in CP-induced nephrotoxicity in rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, there were no significant differences in the normalised K value between the treatment and control groups on days 2 and 7. These preclinical findings add evidence…
Read ArticleIn Sprague-Dawley rats, compared with the Lop group, the abundance of Firmicutes (86.70% vs 91.77%) increased whereas that of Bacteroidetes (7.50% vs 5.26%) and Actinobacteria (3.03% vs 0.81%)…
Read ArticleThis publication examined hydrogen-rich water using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn mice, hypoxia exposure led to changes in the diversity of gut microbiota, along with a decrease in the abundance of aerobic bacteria and beneficial bacteria (e.g., Lactobacillus),…
Read ArticleIn 18 trained participants, the total power output (HRW: 50,866.7 ± 6,359.9W, Placebo: 46,431.0 ± 9,376.5W, p = 0.032) and the total number of repetitions (HRW:78.2 ± 9.5…
Read ArticleIn mice, supplementation with hydrogen-rich water (HW) markedly decreased the severity of oral lesions and preserved epithelial thickness, while restoring the expression of tight junction proteins in the…
Read Article