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416 Articles

Nrf2/HO-1-sulfiredoxin1 pathway involved in nanobubble hydrogen-dissolved water-mediated protective effects by ultrasound-guided early local injection in a rat model of chronic constriction injury-induced neuropathic pain.

By Aug 31, 2026 0 Comments

In rats, ultrasound-guided early local injection of NHW attenuated sciatic nerve injury, alleviated mechanical allodynia and thermal hyperalgesia and inhibited inflammation and oxidative stress damage via the Nrf2/HO-1-sulfiredoxin1 pathway in a rat model of CCI. These preclinical findings add evidence supporting molecular…

Effect of hydrogen-enriched water on healing of excisional full-layer skin wounds in diabetic and non-diabetic rats.

By Aug 31, 2026 0 Comments

In the HRW dressing groups (DH2 and non-DH2), the wound closure rate increased numerically compared to the other groups, and wound healing occurred earlier than the other groups…

Research Progress on Hydrogen-Rich Water in Improving Ocular Surface Diseases and Oxidative Stress

By Aug 31, 2026 0 Comments

This laboratory study evaluated the biological effects of hydrogen-rich water. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to…

Hydrogen gas (H 2), a colorless, tasteless, odorless, non-irritating and highly flammable diatomic gas, has been used in medical applications to prevent decomposition sickness in deep divers. For a long time, H2 was thought to be a “biologically inert gas” which could not

By Aug 31, 2026 0 Comments

In an animal model, the decrease in reperfusion damage improved long term neurological function, such as thermoregulation and weight maintenance, at one week, implying that hydrogen gas can…

Can Hydrogen Therapy Mitigate Cardiovascular Diseases and Support The 8 Essentials of Cardiovascular Health (CVH), of the American Heart Association

By Aug 31, 2026 0 Comments

In a randomized controlled trial involving 60 patients with metabolic syndrome, hydrogen-rich water (HRW) significantly reduced body mass index (BMI), blood lipids, glucose, and HbA1c, and improved inflammatory…

Hydrogen water versus normal saline for post-surgical irrigation: A study on healing and complication rates after third molar extraction.

By Aug 28, 2026 0 Comments

In 30 patients, showed all patients improved over time and that patients in the hydrogen water group had significantly greater improvements in pain, swelling and trismus, as well…

Interaction between gender and post resuscitation interventions on neurological outcome in an asphyxial rat model of cardiac arrest.

By Aug 28, 2026 0 Comments

In this rat model cardiac arrest and CPR, gender did not affect resuscitation but associated with neurological outcome. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes,…

Efficacy and Safety of Hydrogen Therapy in Patients with Early-Stage Interstitial Lung Disease: A Single-Center, Randomized, Parallel-Group Controlled Trial.

By Aug 28, 2026 0 Comments

In 87 patients with early-stage ILD, a significant decrease in CPI and improvement in DLCO-sb were observed in the hydrogen group compared with those in the control group.…

Multiple hits, including oxidative stress, as pathogenesis and treatment target in non-alcoholic steatohepatitis (NASH).

By Aug 28, 2026 0 Comments

In participants, the clinical findings of antioxidant therapies have not always been favorable [ 112 ]. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence…

Carcinostatic effects of alkanoyl ascorbate plus platinum nano-colloid and stabilization of the esterolytically resultant ascorbate by hydrogen.

By Aug 28, 2026 0 Comments

In a laboratory model, although esterolytically converted from Asc6Palm, Asc was necessitated to be retained for efficient carcinostasis, and demonstrated by HPLC-coulometric ECD analysis to be appreciably stabilized…

[Hydrogen-rich water improves progressive sperm motility in rats by reducing oxidative stress and upregulating CLDN3 and SRD5A2 expressions].

By Aug 28, 2026 0 Comments

In rats, compared with the controls, the rats in the HRW group showed markedly decreased oxidative stress-related index CYBB (P < 0.01), increased eNOS level (P < 0.01),…

Editorial: Molecular Mechanism and Therapeutic Approach to Renal Interstitial Fibrosis.

By Aug 28, 2026 0 Comments

This publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.

Protective Effects of Hydrogen-rich Water Intake on Renal Injury in Neonatal Rats with High Oxygen Loading.

By Aug 28, 2026 0 Comments

In rats, hW intake can potentially reduce oxidative stress and prevent renal injury in neonates with high oxygen loading. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…

Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.

By Aug 28, 2026 0 Comments

In male Sprague-Dawley rats, molecular hydrogen-alleviated damage decreased the testicular apoptosis rate and apoptosis protein level, increased sperm motility, increased serum testosterone levels, and improved antioxidative capacity. These…

Impact of nutraceuticals and dietary supplements on mitochondria modifications in healthy aging: a systematic review of randomized controlled trials.

By Aug 28, 2026 0 Comments

This systematic review examined dietary supplements might have reciprocal and multilevel interactions with mitochondria network; however, no systematic review assessed the role of different nutraceuticals in mitochondria modification…