Circulating messenger for neuroprotection induced by molecular hydrogen.

This in vitro or cellular study examined Circulating messenger for neuroprotection induced by molecular hydrogen. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen (H) showed protection against various kinds of oxidative-stress-related diseases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.

This narrative review examined Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?

This narrative review examined Hydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?. The abstract describes Published literature review. The abstract reports: Existing data on the effects of hydrogen on ischemia-reperfusion injury related to organ transplantation are specifically reviewed and coupled with further suggestions for future…. This is an automated editorial draft based on the abstract and requires source review before publication.

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New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State.

This in vitro or cellular study examined New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State. The abstract describes Cell culture / in vitro model. The abstract reports: Several findings indicate that ERW had the ability of a scavenger free radical, which results from hydrogen molecules with a high reducing ability and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles.

This in vitro or cellular study examined The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles. The abstract describes PC12 cell model. The abstract reports: We previously showed that ERW was capable of extending lifespan of Caenorhabditis elegans by scavenging ROS [2]. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss.

This uncontrolled human study examined Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen as an energy source for Helicobacter pylori.

This animal study examined Molecular hydrogen as an energy source for Helicobacter pylori. The abstract describes Mouse model. The abstract reports: We found that hydrogen is available in the gastric mucosa of mice and that its use greatly increased the stomach colonization by H. pylori. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen in Transplantation: Potential Applications and Therapeutic Implications.

This narrative review examined Hydrogen in Transplantation: Potential Applications and Therapeutic Implications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs.

This animal study examined An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs. The abstract describes Animal model. The abstract reports: A HILIC-UHPLC-Q-TOF-MS-based protocol for untargeted metabolomics of perilymph is presented and shown to be fit-for-purpose. We found a clear difference in the perilymph metabolome…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence.

This animal study examined A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence. The abstract describes Mouse model. The abstract reports: Our results link a gut microbiome-produced diffusible metabolite to augmenting bacterial pathogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.

This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.

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Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions.

This narrative review examined Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.

This in vitro or cellular study examined Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial

This randomized controlled trial examined Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial. The abstract describes Human participants; sample size 34; reported duration 10 weeks. The abstract reports: H2 activates ATP-binding cassette transporter A1-dependent efflux, enhances HDL antiatherosclerotic functions, and has beneficial lipid-lowering effects. The present findings highlight the potential role of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.

This animal study examined Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. The abstract describes Mouse model. The abstract reports: We found that H activated the expression of sets of genes regulated by histone H3K27 methylation status. This is an automated editorial draft based on the abstract and requires source review before publication.

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