Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside.

This narrative review examined Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats

This animal study examined Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats. The abstract describes Rat model. The abstract reports: Experimental results showed that a 7-day MSN intervention significantly attenuated anxiety-like behaviors while reversing the synaptic deficits induced by SPS&S in prefrontal cortical regions. This is an automated editorial draft based on the abstract and requires source review before publication.

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Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model

This animal study examined Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. The abstract describes Mouse model. The abstract reports: We have previously demonstrated in the MIA mouse model that maternal administration of H attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.

This animal study examined Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder. The abstract describes Animal model. The abstract reports: Our results showed that increased SDS and SAS indices and decreased alpha diversity indicated more serious mental disorders and lower bacterial diversity in METH…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression

This animal study examined Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression. The abstract describes Mouse model. The abstract reports: The MCDHF I/R group showed higher levels of AST and ALT in serum, TUNEL-positive apoptotic cells, F4/80 immunopositive cells, mRNA levels of inflammatory cytokines,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hypothermic Machine Perfusion with Hydrogen Gas Reduces Focal Injury in Rat Livers but Fails to Restore Organ Function.

This animal study examined Hypothermic Machine Perfusion with Hydrogen Gas Reduces Focal Injury in Rat Livers but Fails to Restore Organ Function. The abstract describes Rat model; reported duration 3 hours. The abstract reports: In conclusion, HMP and H gas treatment are partly effective in DCD rat livers but insufficient. Hypothermic machine perfusion can improve focal microcirculation and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine.

This animal study examined Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine. The abstract describes Porcine model; sample size 14; reported duration 20 min. The abstract reports: H2 gas attenuates markedly ischemia and portal hyperperfusion injury in pigs with massive hepatotectomy, possibly by the reduction of inflammation and oxidative stress, maybe…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

This narrative review examined Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.

This in vitro or cellular study examined Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combination of Cold Storage in a Heavy Water-Containing Solution and Post-Reperfusion Hydrogen Gas Treatment Reduces Ischemia-Reperfusion Injury in Rat Livers

This animal study examined Combination of Cold Storage in a Heavy Water-Containing Solution and Post-Reperfusion Hydrogen Gas Treatment Reduces Ischemia-Reperfusion Injury in Rat Livers. The abstract describes Rat model. The abstract reports: Multiple comparison tests among the UW, Dsol, UW-H, and Dsol-H groups revealed that both treatments, during CS and after reperfusion, conferred a similar extent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation.

This animal study examined Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation. The abstract describes Mouse model; reported duration 4 days. The abstract reports: Therefore, the results of the present study demonstrated that treatment with exogenous H by intraperitoneal injection may alleviate acute alcohol-induced liver injury by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen treatment: a novel option in liver diseases.

This narrative review examined Hydrogen treatment: a novel option in liver diseases. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.

This animal study examined Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. The abstract describes Mouse model; reported duration 90 min. The abstract reports: We have recently showed that molecular hydrogen has great potential for selectively reducing cytotoxic reactive oxygen species, such as hydroxyl radicals, and that inhalation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway

This animal study examined Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway. The abstract describes Mouse model; sample size 6. The abstract reports: Our findings indicate that HCH may protect the liver against I/R injury through the A dependent PI3K-Akt pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver.

This animal study examined Hydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver. The abstract describes Rat model; reported duration 90 min. This is an automated editorial draft based on the abstract and requires source review before publication.

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