Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders
This narrative review examined Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders. The abstract describes Published literature review. The abstract reports: Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals in ischemic stroke, molecular…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
This animal study examined Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. The abstract describes Rat model. The abstract reports: These findings suggest that H augments cellular antioxidant defense capacity through activation of MAPK signaling pathways, leading to HO-1 expression and subsequent upregulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression.
This animal study examined PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression. The abstract describes Mouse model. The abstract reports: The results showed the expression of PPARα was decreased in SAE mice and that activation of PPARα in septic mice improved the survival rate…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.
This uncontrolled human study examined Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro. The abstract describes Human participants. The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
This animal study examined Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperbaric hydrogen therapy improves secondary brain injury after head trauma.
This animal study examined Hyperbaric hydrogen therapy improves secondary brain injury after head trauma. The abstract describes Mouse model; sample size 40; reported duration 90 minutes. The abstract reports: Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePhosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.
This animal study examined Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice. The abstract describes Mouse model. The abstract reports: In proteomics and phosphoproteomics analysis, 268 differentially phosphorylated proteins (DPPs) showed a change in the phosphorylated form in the CLP + H group (p . This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro.
This animal study examined Hydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro. The abstract describes Rat model. The abstract reports: These results indicate that HM effectively reduces HG‑induced oxidative stress in RSCs and protects them against parthanatos. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreUse of molecular hydrogen as an energy substrate by human pathogenic bacteria.
This animal study examined Use of molecular hydrogen as an energy substrate by human pathogenic bacteria. The abstract describes Mouse model. The abstract reports: Pathogenic Helicobacter species (Helicobacter pylori and H. hepaticus) have the ability to use H(2) through a respiratory hydrogenase, and it was demonstrated that the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective and Preventative Effects of Molecular Hydrogen.
This animal study examined Neuroprotective and Preventative Effects of Molecular Hydrogen. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDirect Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions | Bentham Science
This narrative review examined Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions | Bentham Science. The abstract describes Published literature review. The abstract reports: The resulting suppression of Ca2+-signaling inactivates multiple functional NFAT and CREB transcription factors, which may explain H multi-functionality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
This in vitro or cellular study examined Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSi-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission | Medical Technology
This animal study examined Si-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission | Medical Technology. The abstract describes Mouse model. The abstract reports: Such transmissions can result in infections and diseases in infants or the induction of an inflammatory immune response through the placenta. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
This animal study examined Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model. The abstract describes Rat model. The abstract reports: These results support the theory that H has a potential benefit in the prevention of preeclampsia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen resuscitation, a new cytoprotective approach.
This narrative review examined Hydrogen resuscitation, a new cytoprotective approach. The abstract describes Published literature review. The abstract reports: In mammals, endogenous hydrogen is produced as a result of the fermentation of non-digestible carbohydrates by intestinal bacteria and it is absorbed into the…. This is an automated editorial draft based on the abstract and requires source review before publication.
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