Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, hydrogen improved PaO(2)/FIO(2) and PVO(2)/FIO(2) from the arterial and pulmonary venous blood in recipients and decreased the lung injury score in grafts from brain-dead donors. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn the group *exposed to hydrogen gas, vestibular hair cells were morphologically well preserved and their mechano-electrical transduction activities were relatively well maintained when compared with controls. The…
Read ArticleIn Reactive oxygen species (ROS) play a role in the degeneration of auditory hair cells because of aging, noise trauma, or ototoxic drugs, incubation with a hydrogen-saturated medium…
Read ArticleIn an animal model, here, the researchers found that TBI-challenged rats showed significant brain injuries characterized by the increase of BBB permeability, brain edema and lesion volume as…
Read ArticleIn rabbits, after 240 min of reperfusion, intraperitoneal administration of HRS increased PaO2/FiO2 ratio and superoxide dismutase activities, and decreased malondialdehyde contents, proinflammatory cytokines expression, and myeloperoxidase activities,…
Read ArticleIn dogs, among all groups, NAD content and the number of apoptotic and 8-OHdG positive cells was not significantly different, indicating that the cardioprotection afforded by H(2) was…
Read ArticleThe results demonstrated that H₂-treated mice showed significantly shorter escape latency, longer target quadrant duration, and higher NOR index compared to controls. These preclinical findings add evidence supporting…
Read ArticleIn male C57BL/6 mice, hydrogen preconditioning significantly reduced MDA levels and enhanced MnSOD activity, which peaked 24 h postinjury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn Peripheral blood mononuclear cells were isolated using Ficoll solution and labeled with fluorescent antibodies (BD Biosciences, San Jose, CA, USA), after 2 weeks of hydrogen inhalation, statistically…
Read ArticleIn male Wistar rats, fluid resuscitation with 2% hydrogen inhalation decreased serum creatinine, blood urea nitrogen, and neutrophil gelatinase-associated lipocalin. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn 100 patients with brain glioma, similarly, S100β, NSE, GFAP, and MDA levels were found to be lower in the hydrogen group (0.41±0.09 μg/L, 8.24±1.64 ng/mL, 0.71±0.23 pg/mL,…
Read ArticleIn rats, histopathologically, a decrease in degenerative cells was observed in the treatment group (i.e., HI+H₂). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleThe researchers found that the beneficial effects of HS treatment on SAH-induced CV were associated with decreased levels of lipid peroxidation, increased activity of antioxidant enzymes, and reduced…
Read ArticleIn conclusion, HS may inhibit inflammation in EBI and improve neurobehavioral outcome after SAH, partially via inactivation of NF-κB pathway and NLRP3 inflammasome. These preclinical findings add evidence…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
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