Hydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients.
This uncontrolled human study examined Hydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients. The abstract describes Human participants; reported duration 2 days. The abstract reports: Our results suggest that an increase in hydrogen gas production is inversely associated with a reduction of the peripheral blood IL-1β mRNA level after…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage
This in vitro or cellular study examined Hydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage. The abstract describes Lymphocyte cell model. The abstract reports: Compared to cells pretreated without hydrogen, we demonstrated that treating cells with hydrogen-rich PBS before irradiation could significantly inhibit IR-induced apoptosis, increase viability of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases
This narrative review examined Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases. The abstract describes Published literature review. The abstract reports: All these pathological damages are concomitant with overproduction of reactive oxygen species (ROS) where molecular hydrogen has been widely demonstrated as a selective antioxidant. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
This animal study examined Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. The abstract describes Mouse model; reported duration 60 min. The abstract reports: CLP mice showed obvious brain injury characterized by aggravated pathological damage, BBB disruption and brain edema at 24h after CLP operation, which was markedly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway.
This uncontrolled human study examined Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. The abstract describes Human participants. The abstract reports: The results of MTT indicated that H2 and RAP could increase cell viability after OGD/R treatment, while 3-MA further aggravated injury and inhibited the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCoadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
This animal study examined Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice. The abstract describes Mouse model; sample size 8. The abstract reports: Western blot analysis showed that coadministration of 1.3% hydrogen gas significantly (P < 0.001) reduced the level of neuronal apoptosis to approximately 40% compared…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTransperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity.
This uncontrolled human study examined Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity. The abstract describes Human participants. The abstract reports: Trans-peritoneal administration of H2 reduces peritoneal and systemic OS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMechanism of influence of molecular hydrogen on the function of the proximal tubule of the nephron in irritatable bowel syndrome | Journal of Education, Health and Sport
This uncontrolled human study examined Mechanism of influence of molecular hydrogen on the function of the proximal tubule of the nephron in irritatable bowel syndrome | Journal of Education, Health and Sport. The abstract describes Human participants; sample size 60; reported duration 7 days. The abstract reports: Statistical data processing was performed using computer programs "Statgrafics"and "Exel 7.0".Results and discussion. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
This in vitro or cellular study examined The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species. The abstract describes Mouse model. The abstract reports: Recently, the production of mitochondrial reactive oxygen species (mtROS) in macrophages stimulated with LPS has been suggested to act as a trigger during the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOpen-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
This randomized controlled trial examined Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies. The abstract describes Human participants; sample size 10; reported duration 12 weeks. The abstract reports: Hydrogen-enriched water improves mitochondrial dysfunction in MM and inflammatory processes in PM/DM. Less prominent effects with the double-blind trial compared to the open-label trial…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
This animal study examined Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats. The abstract describes Rat model. The abstract reports: The data showed that the spatial recognition memory and fear memory of the rats treated with sevoflurane decreased compared with the control, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreModulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.
This uncontrolled human study examined Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision. The abstract describes Human participants; reported duration 3 months. The abstract reports: Overall results demonstrated that an optimal oxidative balance can be restored and GERD symptoms can be reduced rapidly via the integration of ERW in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
This uncontrolled human study examined Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase. The abstract describes Human participants. The abstract reports: We found that hydrogen-rich medium could inhibit adhesion of monocytes to endothelial cells and decrease levels of adhesion molecules, whereas the levels of transepithelial/endothelial…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
This animal study examined Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy. The abstract describes Rat model; reported duration 1 hour. The abstract reports: These results revealed a better protective effect of hydrogen on myocardial ischemic/reperfusion injury in rats by attenuating endoplasmic reticulum stress and down-regulating autophagy compared…. This is an automated editorial draft based on the abstract and requires source review before publication.
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