Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, nissl staining demonstrated a significant decrease in the number of nissl-stained dark neurons (N-DNs) in HI group compared to TBI group at 2 h post-TBI, and the TBI-induced neuronal loss was attenuated by HI at day 3 post-TBI.…
Read ArticleIn rats, effect of hydrogen on S100- β and NSE levels The levels of S100-β and NSE have similar trends, these increased in the I/R group compared with…
Read ArticleIn Sprague-Dawley rats, bcl-2 was significantly increased while Bax and cleaved caspase-3 was decreased by HS treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement…
Read ArticleIn rats, at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration, serum malondialdehyde content,…
Read ArticleIn rats, these results demonstrated that H₂ significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the IR group.…
Read ArticleIn Sprague-Dawley rats, hydrogen administration reduced the expression of 8-OHdG in the brain, but did not attenuate brain water content or improve functional outcome, regardless of administration route.…
Read ArticleThese results show that molecular hydrogen given in drinking water reverses many of the sequelae of CCI and suggests that it could be an easily administered, highly effective…
Read ArticleIn a laboratory model, hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved…
Read ArticleIn male Sprague-Dawley rats, hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn a laboratory model, hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx.…
Read ArticleIn mice, the hydrogen inhalation reduced these effects acutely (24 h); however it exhibited only a tendency to improvement in the delayed study (72 h). These preclinical findings…
Read ArticleIn rats, the beneficial effects of hydrogen-rich saline were associated with decreased levels of oxidative products, as well as the increased levels of antioxidant enzymes. These preclinical findings…
Read ArticleIn rats, rats undergone global cerebral I/R and treated with HRS have milder injury than I/R animals without HRS treatment. miR-210 expression in the hippocampus of the I/R…
Read ArticleIn an animal model, treatment with hydrogen-rich saline, which elevated the levels of molecules associated with brain-derived neurotropic factor (BDNF)-mediated synaptic plasticity, improved cognitive performance in the Morris…
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