Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, hydrogen gas can reduce cytotoxic reactive oxygen species (ROS) that are produced in inflamed tissues. The authors concluded that experimental results indicate that the Lip NR system that can photosynthesize H₂ gas has great potential for mitigating oxidative…
Read ArticleIn the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression increased, but IL-1beta and…
Read ArticleIn mice, all parameters of inflammation (foot volume, infiltration of neutrophils, amount of TNF-α and the level of TNF-α's mRNA) were attenuated by the hydrogen saline treatment. These…
Read ArticleIn The researchers previously showed that H₂ acts as a novel antioxidant to protect cells against oxidative stress, exposure of cultured cells to the H₂-dependently autoxidized phospholipid species…
Read ArticleIn mice, at day-7, DSS-induced pathogenic outcomes including, loss of body weight, increase of colitis score, pathogenic shortening of colon length, elevated level of IL-12, TNF-alpha and IL-1beta…
Read ArticleIn a laboratory model, H₂ treatment dose-dependently attenuated the increased levels of pro-inflammatory cytokines (TNF-α, IL-1β, HMGB1), but further increased the level of anti-inflammatory cytokine IL-10 at 3…
Read ArticleThe researchers found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn guinea pigs, both the number and biological activity of CD4+CD25+Foxp3+Treg cells increased with up-regulation of Th1/Th2 after hydrogen-rich saline administration. These preclinical findings add evidence supporting molecular…
Read ArticleIn This ex vivo study investigated whether ECMO could serve as an effective vehicle for hydrogen delivery, hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p =…
Read ArticleIn Standard treatments frequently fall short in effectively controlling symptoms, highlighting the need for innovative therapeutic approaches, the patient received daily hydrogen capsules, which resulted in an increased…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen selectively targets harmful radicals, and EHW intake helps balance stress-induced hormonal dysregulation, potentially easing disorders associated with chronic stress.…
Read ArticleIn mice, enzyme-linked immunosorbent assay performed on day 7 revealed that hydrogen water reduced the level of the pro-inflammatory cytokine interleukin-6 and increased that of forkhead box P3…
Read ArticleIn a laboratory model, the EWP may use a gargle solution and a soaking solution for prevention of oral candidiasis and denture-related stomatitis due to antifungal activity. (J…
Read ArticleIn rats, increased post-void residual volume in obstructed rats was significantly reduced by H₂ water. There was no significant difference in histological findings between rats with bladder obstruction…
Read ArticleIn the study, the researchers performed a comparative evaluation of two groups with largely equal (i.e., no significant difference) relative abundances of Bifidobacterium who drank either AEW containing…
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