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This in vitro or cellular study examined Protective effects of glutathione on oxidative injury induced by hydrogen peroxide in intestinal epithelial cells. The abstract describes Epithelial cell model. The abstract reports: GSH appears to ameliorate oxidative injury in intestinal epithelial cells by…
Read ArticleThe researchers found hydrogen-rich solutions treatment groups showed the decreased MDA, MPO, IL-6 and TNF-α levels, and increased SOD, IL-10 comparing with those of non-hydrogen solutions administration groups.…
Read ArticleIn rats, iR-induced upregulation of proinflammatory cytokine mRNAs such as IL-6 was mitigated by hydrogen treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn rats, increased expression of TJ proteins occludin and ZO-1 by reducing various parameters of ERS and ERS-induced apoptosis evidenced by down-regulation of the protein levels of GRP78,…
Read ArticleIn rats, hRSS is effective in reducing the intestinal damage caused by an IRI: HRSS has the potential to reduce the detrimental effects of intestinal anastomosis performed after…
Read ArticleIn rats, however, hydrogen-rich saline treatment significantly increased the 24-h survival of rats to 53.33% (8 of 15 rats) in the HRS1 group and 86.67% (13 of 15…
Read ArticleIn This study utilized next-generation sequencing (NGS) to assess mRNA and miRNA expression in EHW-treated Caco-2 cells, eHW treatment significantly decreased the levels of miR-429 and miR-200c-3p and…
Read ArticleIn rats, this study provides biochemical and histomorphological evidence that HRSS prevents intestinal damage in I/R injury caused by volvulus. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, meanwhile, the increased MPO level in the EHW-administered group significantly reduced 2 ( p = 0.0011) and 4 ( p = 0.0009) days post TNBS treatment…
Read ArticleIn rats, the authors' present study showed that hydrogen treatment lessened the stress-induced lipid peroxidation, protein carbonyl and DNA oxidant and improved tissue antioxidant potential. These preclinical findings…
Read ArticleIn In conclusion, H₂ could protect IPEC-J2 cells from DON-induced oxidative damage and apoptosis in vitro, however, H₂ efficiently reduced the LDH release ( p < 0.05) and…
Read ArticleIn rats, plasma cytokines concentrations were reduced in H₂ saline-treated TP rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn mice, bowel dysmotility, induced by surgical manipulation and inflammatory events, was significantly attenuated by intra-abdominal administration of hydrogen-rich saline. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, although enhanced MDA levels were observed in all of the injured animals, the elevation appeared to be significantly inhibited by hydrogen-rich saline treatment ( P <…
Read ArticleThe researchers found that hydrogen treatment significantly improved multiple symptoms of chronic pancreatitis. These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential…
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