Molecular hydrogen is a potential protective agent in the management of acute lung injury.

This uncontrolled human study examined Molecular hydrogen is a potential protective agent in the management of acute lung injury. The abstract describes Human participants. The abstract reports: Several studies have demonstrated the preventive and therapeutic effects of molecular hydrogen in the various diseases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.

This uncontrolled human study examined Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated that inhaled hydrogen reduced transplant-induced lung injury and induced heme oxygenase (HO)-1. This is an automated editorial draft based on the abstract and requires source review before publication.

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Can Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study.

This uncontrolled human study examined Can Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Treatment with HRW in patients with hypoxia from chronic lung diseases may decrease oxidative stress and improve oxygen saturation in some patients. HRW therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota.

This uncontrolled human study examined Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Hydrogen-rich water may alleviate CINP by affecting the diversity and structure of the gut microbiota, and then the LPS-TLR4 pathway, which provides a direction…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen and radiation protection

This randomized controlled trial examined Molecular hydrogen and radiation protection. The abstract describes Human participants. The abstract reports: A randomised, placebo-controlled investigation also showed consumption of H(2) can improve the quality of life of patients treated with radiotherapy for liver tumours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water.

This uncontrolled human study examined Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Particularly, hydrogen-rich water showed a promising reduction in these symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study

This randomized controlled trial examined Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: This pilot study revealed that the inhalation of molecular hydrogen gas was safe, but did not show any beneficial effects in patients with PD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial

This randomized controlled trial examined Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial. The abstract describes Human participants; sample size 9; reported duration 48 weeks. The abstract reports: The results indicated that drinking H₂-water was safe and well tolerated, and a significant improvement in total UPDRS scores for patients in the H₂-water…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease.

This randomized controlled trial examined Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.

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Realizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease.

This case report or case series examined Realizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 35 years. The abstract reports: Fox Foundation has been funding research on Parkinson's disease for 35 years, but has yet to find a cure. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia.

This uncontrolled human study examined Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study.

This uncontrolled human study examined Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study. The abstract describes Human participants; sample size 18; hydrogen delivered as hydrogen water. The abstract reports: This novel, proof-of-concept study demonstrated that PBM+H2 therapy is safe and reduces disease severity. A larger-scaled clinical trial is warranted to completely investigate the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Antioxidant effects of continuous intake of electrolyzed hydrogen water in healthy adults.

This observational study examined Antioxidant effects of continuous intake of electrolyzed hydrogen water in healthy adults. The abstract describes Human participants; sample size 64; hydrogen delivered as hydrogen water. The abstract reports: These results suggest that the continuous intake of EHW induces antioxidant effects and may contribute to alleviate the risk of various oxidative stress-related dysfunctions…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study

This randomized controlled trial examined The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study. The abstract describes Human participants; sample size 37; hydrogen delivered as hydrogen inhalation. The abstract reports: Their results were compared to those of the control group participants who did not undergo HIT. This is an automated editorial draft based on the abstract and requires source review before publication.

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Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis

This uncontrolled human study examined Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: This procedure can improve survival after sepsis through mitigating the sepsis-induced organ failure by inhibiting oxidative stress, apoptosis, and inflammatory pathways. Peritoneal lavage with…. This is an automated editorial draft based on the abstract and requires source review before publication.

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