Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
This in vitro or cellular study examined Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intraperitoneal administration of H2-rich saline resulted in large increases in H2 concentration in the IVC ranging from 0.00183 mg/L (0.114%) to 0.00725 mg/L (0.453%). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells.
This in vitro or cellular study examined Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells. The abstract describes A549 cell model. The abstract reports: Results show that time-dependent administration of 2% H gas recovered the cells from oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells.
This in vitro or cellular study examined Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. The abstract describes Cell culture / in vitro model. The abstract reports: Meanwhile hydrogen showed no such effects on cell proliferation and TNF-α expression, but it could affect the level of hCG, indicating hydrogen as a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS
This in vitro or cellular study examined Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS. The abstract describes Cell culture / in vitro model. The abstract reports: Recent research has demonstrated that NEMP can disrupt the male reproductive system. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.
This in vitro or cellular study examined Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation. The abstract describes Lymphocyte cell model. The abstract reports: In conclusion, these data showed that H(2) attenuated (12)C(6+) radiation-induced cell apoptosis through reducing the ROS level and modulating apoptotic molecules, thus indicating the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen protects auditory hair cells from cisplatin-induced free radicals.
This in vitro or cellular study examined Hydrogen protects auditory hair cells from cisplatin-induced free radicals. The abstract describes Cell culture / in vitro model. The abstract reports: Additionally, hydroxyphenyl fluorescein (HPF) staining of the spiral ganglion showed that formation of hydroxyl radicals was successfully reduced in hydrogen-treated cochleae. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes
This in vitro or cellular study examined Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. The abstract describes HaCaT keratinocyte model. The abstract reports: Our results showed that H exerted cytoprotective effects against stress induced by HO, t-BuOOH, and glyoxal. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease
This in vitro or cellular study examined Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease. The abstract describes Cell culture / in vitro model. The abstract reports: Thus, it is strongly suggested that hydrogen might provide a great advantage to prevent or minimize the onset and progression of PD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water
This in vitro or cellular study examined Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. The abstract describes HT1080 cell model. The abstract reports: ERW has reactive oxygen species (ROS)-scavenging activity and recent studies demonstrated that hydrogen-dissolved water exhibits ROS-scavenging activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.
This in vitro or cellular study examined Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.
This in vitro or cellular study examined Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction. The abstract describes Cell culture / in vitro model. The abstract reports: As a result, H protected the cultured cells against the cytotoxic effects induced by -butyl hydroperoxide; H suppressed cellular fatty acid peroxidation and cell…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells.
This in vitro or cellular study examined Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells. The abstract describes PC12 cell model. The abstract reports: The data showed that H2 promoted the cell viability and inhibited the damage in the cell and mitochondria membrane, reduced the levels of lipid…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice.
This in vitro or cellular study examined Hydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice. The abstract describes Cell culture / in vitro model. The abstract reports: These findings suggest that molecular hydrogen attenuates HFHSD-induced metabolic disturbances primarily through suppression of adipose inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria.
This in vitro or cellular study examined Molecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria. The abstract describes Stem-cell model. The abstract reports: This study reveals the application potential of H in skeletal muscle diseases or other pathologies related to mitochondrial dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells.
This in vitro or cellular study examined PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells. The abstract describes Cell culture / in vitro model. The abstract reports: Using inhibitor of p38, we found that regulation of the p38/glycogen synthase kinase 3β (GSK3β)/Nrf-2 axis was involved in the protective effects of PGC-1α. This is an automated editorial draft based on the abstract and requires source review before publication.
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