Assessment of antibacterial effect of hydrogen water on plaque from patients with chronic periodontitis.
In 20 patients, hydrogen water showed antibacterial activity against aerobic and anaerobic organisms associated with chronic periodontitis. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreTwo-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study.
In In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a sin, although supplementation of H₂ has been reported to increase mitochondrial metabolism in animal studies, the effects of the administration of H₂ on aerobic capacity during exercise in humans are still not clear. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence exercise performance and recovery.
Read More[Changes of nasal nitric oxide in the treatment of allergic rhinitis with hydrogen-rich saline lavage of nasal cavity].
In 20 patients with moderate to severe persistent allergic rhinitis were enrolled, hydrogen-rich saline lavage can cause nNO change in nasal cavity which may be used in the treatment of allergic rhinitis. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreHydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males.
In 8 participants, however, HW suppressed the reduction in biological antioxidant potential/diacron-reactive oxygen metabolites observed in PW. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreHydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.
In 24 patients, no significant toxicity was observed. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read MoreThe Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial.
In 60 participants (30 men and 30 women) with metabolic syndrome, supplementation with high-concentration HRW significantly reduced blood cholesterol and glucose levels, attenuated serum hemoglobin A1c, and improved biomarkers of inflammation and redox homeostasis as compared to placebo.
Read MoreEffects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial.
In participants, there was a further reduction in measured pro-inflammatory cytokine scores, improving body pain and physical health. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation.
Read MoreHydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial.
In 21 patients with laboratory-confirmed COVID-19 from seven hospitals in China, inhalation of hydrogen/oxygen mixed gas (H₂ -O₂ ) might have a role in the treatment of COVID-19 given the decreased resistance compared with room air when passing through the airways. This open-label study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
Read MoreThe Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial.
In 60 participants (30 men and 30 women) with metabolic syndrome, supplementation with high-concentration HRW significantly reduced blood cholesterol and glucose levels, attenuated serum hemoglobin A1c, and improved biomarkers of inflammation and redox homeostasis as compared to placebo.
Read MoreElectrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis.
In 42 patients with ERW for 1 year, the intracellular IL-2 and IFN-gamma levels in the Th1/Tc1 cells significantly (P < 0.05) increased and the intracellular IL-4, IL-6 and IL-10 levels in the Th2/Tc2 cells decreased. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation.
Read More[Clinical study of hydrogen-rich saline in the treatment of moderate to severe allergic rhinitis].
In 20 patients with hydrogen-rich saline in the treatment of moderate to severe allergic rhinitis, hydrogen-enriched saline is safe and effective for allergic rhinitis. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read MoreMolecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.
In 5 patients, HRW was not superior to placebo in preventing clinical worsening at day 14: in the H₂ group, 46.1% in the H₂ group, 43.5% in the placebo group, hazard ratio 1.09, 90% confidence interval [0.90-1.31]. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read More[Protective effect of hydrogen on the lung of sanitation workers exposed to haze].
Hydrogen inhalation improved cough and was associated with changes in respiratory and inflammatory biomarkers among sanitation workers exposed to haze.
Read MoreEffects of Topical Hydrogen Purification on Skin Parameters and Acne Vulgaris in Adult Women.
The study evaluated 30 women with high sebum and acne and a healthy comparison group of 30 women with low sebum. After four weekly treatments using alkaline water generated by a Hebe Hydrogenium+ device, sebum decreased and moisture increased. The comparison group was not a randomized sham-treatment control, and the original report did not include a dissolved molecular-hydrogen dose.
Read MoreHydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients.
In 2 patients, the induction of hydrogen gas production and the reduction in peripheral blood IL-1β mRNA after the test meal were not significant between days 1 (without acarbose) and 2 (with acarbose). These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
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