[The combined use of inhaled nitric oxide and molecular hydrogen in patients with post-COVID-19 syndrome].
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence fatigue-related outcomes.
Read MoreMolecular hydrogen generated by elemental magnesium supplementation alters rumen fermentation and microbiota in goats.
The researchers tested the hypotheses that supplementation of a diet with elemental Mg increases ruminal dissolved H₂ (dH2) in rumen fluid, which in turn alters rumen fermentation and microbial community in goats. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreRandomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen.
The researchers found that administering a persistent H₂-generating supplement increased the human exhaled H₂ concentration (p < 0.01) and improved tear stability (p < 0.01) and dry eye symptoms (p < 0.05) significantly. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreEffect of CO2 and H2 gas mixture in cold water immersion on recovery after eccentric loading.
In 34 healthy participants, CO₂/H₂ cold-water immersion helped preserve isometric strength, countermovement-jump height, and range of motion after eccentric exercise compared with the other recovery conditions. Muscle soreness increased after exercise in every group, indicating that the recovery effect did not extend to every measured outcome. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence exercise performance and recovery in healthy adults.
Read MoreHydrogen Rich Water Improved Ventilatory, Perceptual and Lactate Responses to Exercise.
A significantly lower blood lactate was found with HRW (4.0±1.6 and 8.9±2.2 mmol.l-1) compared to Placebo (5.1±1.9 and 10.6±3.0 mmol.l-1) at 3.0, and 4.0 W.kg-1, respectively.
Read MoreRandomized, double‐blind, multicenter trial of hydrogen water for Parkinson’s disease
Randomized, double‐blind, multicenter trial of hydrogen water for Parkinson's disease A previous randomized, doubleblind study showed that drinking 1,000 mL of H₂ water per day for 48 weeks significantly improved the total Unified Parkinson’s Disease Rating Scale (UPDRS) scores of patients with PD and treated with levodopa. The researchers conducted a longer and larger scale H₂ water trial that also included patients who were not treated with levodopa.
Read MoreAcute effect of hydrogen-rich water on physical, perceptual and cardiac responses during aerobic and anaerobic exercises: a randomized, placebo-controlled, double-blinded cross-over trial.
In In a randomized, double-blind study design, all players ingested 500 mL of HRW or placebo (PLA) supplement 30 min before the start of the tests, 500 mL of HRW can significantly improve HRpeak, time to exhaustion, RPE, with no significant effect on MAS, jumping performance in amateur endurance athletes. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read More“Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients.
In 82 patients with stage III and IV cancer treated with hydrogen inhalation using the "real world evidence" method, of the 58 cases with one or more abnormal tumor markers elevated, the markers were decreased at 13-45 days (median 23 days) after hydrogen inhalation in 36.2%.
Read MorePsychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture.
Six commercial divers were evaluated during an open-sea dive to 500 meters while breathing a mixture containing 49% hydrogen together with helium and oxygen. The study reported moderate high-pressure nervous-system symptoms and detectable narcotic effects of hydrogen while the divers completed the operational dive. It is included as related safety and physiology background because this extreme hyperbaric exposure was not a therapeutic hydrogen treatment and cannot be generalized to clinical use.
Read MoreHydrogen-Nano-Bubble-Rich Water in Bucket/Bathtub Improves Intractable Skin Roughness
Hydrogen-Nano-Bubble-Rich Water in Bucket/Bathtub Improves Intractable Skin Roughness They were also treated with an electrolyzer composed of a lattice-shaped, microscopically flat, platinum-plated three-layer electrode, except for one subject who was treated with a micro-porous emittance terminal hydrogen-jetting apparatus, resulting in improvements in both cases.
Read MoreDesign of a Functional Eye Dressing for Treatment of the Vitreous Floater.
This study evaluated a functional eye dressing designed to deliver both molecular hydrogen and oxygen around the eye. In uncontrolled clinical observations involving 28 patients, the authors reported improvement in sensory-floater symptoms. Because the dressing delivered two gases and the study did not include a controlled comparator, the contribution of molecular hydrogen cannot be isolated.
Read MoreAbstract 10368: The Safety and Tolerability of Prolonged Inhalation of Hydrogen Gas in Air: A Phase I Clinical Trial
Abstract 10368: The Safety and Tolerability of Prolonged Inhalation of Hydrogen Gas in Air: A Phase I Clinical Trial There were no significant changes in PFTs (B), MMSE scores (C), EKG measurements (D) or serologic tests for hematologic (except for clinically-insignificant increases in hematocrit and platelet counts), renal, hepatic, pancreatic, or cardiac injury (E) associated with H₂ inhalation.
Read MoreEffect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults.
In 100 healthy participants with no adverse events, after exercise-induced dehydration, consumption of the electrolyzed, high-pH water reduced high-shear viscosity by an average of 6.30% compared to 3.36% with standard purified water (p = 0.03). These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read MoreAcute ingestion of hydrogen-rich water does not improve incremental treadmill running performance in endurance-trained athletes.
In This randomized controlled trial examined the effects of H₂-water ingestion on physiological responses and exercise performance during incremental treadmill running, cardiorespiratory responses, RPE, and blood gas indices were not significantly different at each submaximal running intensity (range: 34%-91% maximal oxygen uptake) between H₂-water and placebo trials. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreSupersaturated Hydrogen-Rich Water Hydrotherapy for Recovery of Acute Injury to the Proximal Phalanges on the 5th Toe: A Case Report
In 57 participants, this case is yet another indication that high-concentration hydrogen-rich hydrotherapy may be a helpful first line treatment in terms of reduction of pain and improvement in function following injury, in addition to the evidence suggesting benefit in reducing chronic indications caused by acute or chronic stress. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
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