Hydrogen intake relieves alcohol consumption and hangover symptoms in healthy adults: a randomized and placebo-controlled crossover study.
In 1 participants, hydrogen treatment improved cognitive testing scores (P< 0.05), including attention and executive functions. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence cognitive function in healthy adults.
Read MoreEffectiveness of oral and topical hydrogen for sports-related soft tissue injuries.
In 2013 participants, oral and topical hydrogen intervention was found to augment plasma viscosity decrease as compared with the control group (P = 0.04). These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation.
Read MoreMolecular hydrogen for outpatients with Covid-19 (Hydro-Covid): a phase 3, randomised, triple-blinded, adaptive, placebo-controlled, multicentre trial
In 2 patients, due to its antioxidative, anti-inflammatory, anti-apoptosis, and antifatigue properties, molecular hydrogen (H₂ ) is potentially a novel therapeutic gas for acute coronavirus disease 2019 (COVID-19) patients. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read MoreImproved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study.
These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreHydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial.
In 21 patients with laboratory-confirmed COVID-19 from seven hospitals in China, inhalation of hydrogen/oxygen mixed gas (H₂ -O₂ ) might have a role in the treatment of COVID-19 given the decreased resistance compared with room air when passing through the airways. This open-label study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
Read MoreHydrotherapy with hydrogen-rich water compared with RICE protocol following acute ankle sprain in professional athletes: a randomized non-inferiority pilot trial.
This pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
Read MoreEffects of inhalation of the hydrogen-rich gas before sleep on fatigue recovery in healthy adults
In 100 healthy participants with no sleep disorders, no significant difference in the percent change of HRV paraments (i.e., LF/HF, RMSSD, SDNN, LF average, HF average, VLF average) and KSS scale from night to morning were observed between CS and HS ( p > 0.67). These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read MoreSupplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.
In 30 patients with T2DM controlled by diet and exercise therapy and 6 patients with IGT, hydrogen-rich water intake was also associated with a trend of decreased serum concentrations of oxidized LDL and free fatty acids, and increased plasma levels of adiponectin and extracellular-superoxide dismutase.
Read MoreSupplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.
In 30 patients with T2DM controlled by diet and exercise therapy and 6 patients with IGT, hydrogen-rich water intake was also associated with a trend of decreased serum concentrations of oxidized LDL and free fatty acids, and increased plasma levels of adiponectin and extracellular-superoxide dismutase.
Read MoreSupplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.
In 30 patients with T2DM controlled by diet and exercise therapy and 6 patients with IGT, hydrogen-rich water intake was also associated with a trend of decreased serum concentrations of oxidized LDL and free fatty acids, and increased plasma levels of adiponectin and extracellular-superoxide dismutase.
Read MoreMolecular hydrogen exposure improves functional state of red blood cells in the early postoperative period: a randomized clinical study.
In 20 patients with 20 patients referring to the Specialized Cardiosurgical Clinical Hospital, H₂ inhalation leads to improvement of functional state of red blood cells, which is accompanied by a more favorable course of the early postoperative period. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreThe Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction – First Pilot Study in Humans.
In this pilot study, hydrogen inhalation during percutaneous coronary intervention was feasible and safe and may have promoted favorable left-ventricular remodeling six months after STEMI. This small, open-label, pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
Read MoreHydrotherapy with hydrogen-rich water compared with RICE protocol following acute ankle sprain in professional athletes: a randomized non-inferiority pilot trial.
This pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
Read MoreEffects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study.
In 27 patients with diarrhea-predominant IBS were randomly allocated to two groups, the IBS quality-of-life score significantly improved from 57.2 to 30.8 in the ARW group; this improvement was significantly greater than the slight improvement from 48.7 to 42.2 observed in the control group (p = 0.029). The abdominal pain score improved from 1.8 to 0.9 in the ARW group and from 1.8 to 1.1 in the control group, with no significant group difference (p = 0.232). These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreOutcomes Assessment of Sustainable and Innovatively Simple Lifestyle Modification at the Workplace – Drinking Electrolyzed-Reduced Water (OASIS-ERW): A Randomized, Double-Blind, Placebo-Controlled Trial.
In 65 participants, of the primary outcome variables assessed, diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential showed a significant interaction between the groups and time, with d-ROMs levels significantly decreased at 8 weeks in ERW compared to those in MW. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence oxidative-stress regulation in healthy adults.
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