Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
This animal study examined Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway. The abstract describes Mouse model. The abstract reports: These results suggest that the LKB1-AMPK-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H, further supporting the idea that H…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria.
This in vitro or cellular study examined Molecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria. The abstract describes Stem-cell model. The abstract reports: This study reveals the application potential of H in skeletal muscle diseases or other pathologies related to mitochondrial dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.
This uncontrolled human study examined Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro. The abstract describes Human participants. The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro.
This animal study examined Hydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro. The abstract describes Rat model. The abstract reports: These results indicate that HM effectively reduces HG‑induced oxidative stress in RSCs and protects them against parthanatos. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNew Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State.
This in vitro or cellular study examined New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State. The abstract describes Cell culture / in vitro model. The abstract reports: Several findings indicate that ERW had the ability of a scavenger free radical, which results from hydrogen molecules with a high reducing ability and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
This in vitro or cellular study examined Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.
This in vitro or cellular study examined Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.
This in vitro or cellular study examined Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis. The abstract describes Lymphocyte cell model. The abstract reports: These results indicate that H(2) released from intestinal bacteria can suppress inflammation induced in liver by ConA. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.
This in vitro or cellular study examined Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing the intracellular acetaldehyde, a toxic substance produced by ethanol degradation, in hepatocyte…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells.
This in vitro or cellular study examined Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Some clinical evidence suggests that H may alleviate fatty liver disease, but the precise molecular mechanisms, particularly the regulation of lipid droplet (LD) metabolism,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen attenuated oxidized low-density lipoprotein-induced inflammation through the stimulation of autophagy via sirtuin 1.
This in vitro or cellular study examined Hydrogen attenuated oxidized low-density lipoprotein-induced inflammation through the stimulation of autophagy via sirtuin 1. The abstract describes Cell culture / in vitro model. The abstract reports: Hydrogen has been demonstrated to serve a protective role in diverse models of disease. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
This in vitro or cellular study examined Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. The abstract describes Cell culture / in vitro model. The abstract reports: We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHeme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.
This in vitro or cellular study examined Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen exerts a regulating role in the release of pro- and anti-inflammatory cytokines in LPS-stimulated macrophages, and this effect is at least partly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.
This animal study examined Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that oral intake of hydrogen-rich water abolishes an immediate-type allergic reaction in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.
This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.
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