Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
This in vitro or cellular study examined Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. The abstract describes HUVEC model; hydrogen delivered as hydrogen water. The abstract reports: H2has long-lasting antioxidant and anti-aging effects on vascular endothelial cells through the Nrf2 pathway, even after transient exposure to H2. Hydrogen-rich water may thus…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy
This in vitro or cellular study examined Electrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEnzyme-Triggered Size-Switchable Nanosystem for Deep Tumor Penetration and Hydrogen Therapy.
This in vitro or cellular study examined Enzyme-Triggered Size-Switchable Nanosystem for Deep Tumor Penetration and Hydrogen Therapy. The abstract describes Cell culture / in vitro model. The abstract reports: The poor penetration of nanocarriers within tumor dense extracellular matrices (ECM) greatly restricts the access of anticancer drugs to the deep tumor cells, resulting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
This uncontrolled human study examined Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen gas has been found to affect a variety of diseases; however, the effect of hydrogen gas on patients with lung cancer has not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response.
This in vitro or cellular study examined Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response. The abstract describes Cell culture / in vitro model. The abstract reports: We found that hydrogen enhances proliferation of four out of seven human cancer cell lines (the responders). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer.
This uncontrolled human study examined Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Similarly, the results of the present study demonstrated that administration of the two agents in combination may inhibit phospho‑Akt activity, and reduce expression of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhibitory effect of electrolyzed reduced water on tumor angiogenesis.
This in vitro or cellular study examined Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. The abstract describes A549 cell model. The abstract reports: Numerous reports have demonstrated that the intracellular redox (oxidation/reduction) state is closely associated with the pattern of VEGF expression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro
This in vitro or cellular study examined Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that KYSE-70 cells and HEEpiCs were generally inhibited by H-silica administration, and there was a significant proliferation-inhibitory effect in an H-silica…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhibits lung cancer progression through targeting SMC3.
This uncontrolled human study examined Hydrogen gas inhibits lung cancer progression through targeting SMC3. The abstract describes Human participants. The abstract reports: Results showed that H inhibited cell viability, migration and invasion, and catalyzed cell apoptosis and H induced A549 and H1975 cells G2/M arrest. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4
This in vitro or cellular study examined Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4. The abstract describes Fibroblast model. The abstract reports: We have previously demonstrated that combined treatment with dissolved hydrogen molecule (H) and platinum nanocolloid (Pt-nc) has carcinostatic effects and that increased intracellular reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSuppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis.
This in vitro or cellular study examined Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis. The abstract describes A549 cell model. The abstract reports: Our previous study found that hydrogen gas (H) could efficiently inhibit lung cancer progression; however, the underlying mechanisms still remains to be elucidated. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
This in vitro or cellular study examined Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Previous evidence suggests Aβ-induced neurotoxicity is linked to the stimulation of reactive oxygen species (ROS) production. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress
This in vitro or cellular study examined Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress. The abstract describes Keratinocyte model. The abstract reports: In the present study, HO dose-dependently impaired the adenosine triphosphate (ATP)-induced Ca response, which was partially protected via co-treatment with β-mercaptoethanol, resulting in reduced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence.
This in vitro or cellular study examined Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
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