Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
This animal study examined Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.
This uncontrolled human study examined Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. The abstract describes Human participants. The abstract reports: Inhalation of hydrogen (H(2)) gas has been demonstrated to limit the infarct volume of brain and liver by reducing ischemia-reperfusion injury in rodents. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury.
This animal study examined Protein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells
H(2) is a therapeutic antioxidant that can reduce oxidative stress. Oxidized low-density lipoprotein, which plays roles in atherosclerosis, may promote endothelial dysfunction by binding the cell-surface receptor LOX-1. LOX-1 expression can be upregulated by various stimuli, including TNF-α.
Read MoreHydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
This animal study examined Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: HW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats
This animal study examined Hydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Based on its inhibition of oxidative stress and up-regulation of anti-oxidative enzymes, we conclude that hydrogen-rich saline is a potentially valuable therapeutic modality for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas protects against myocardial stunning and infarction in swine
This animal study examined Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine. The abstract describes Porcine model. The abstract reports: Inhalation of 2% H(2) gas improves myocardial stunning, and inhalation of 4% but not 2% H(2) gas reduces myocardial infarct size in swine. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImage-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles.
This animal study examined Image-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles. The abstract describes Rat model. The abstract reports: However, H is sparingly soluble in water, resulting in its poor bioavailability in blood and damaged tissues. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water.
This animal study examined Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water may inhibit the apoptosis of cardiomyocytes after ischaemia-reperfusion by upregulating the expression of the JAK2-STAT3 signalling pathway, which reduces ischaemia-reperfusion injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePost-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.
This animal study examined Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. The abstract describes Rat model. The abstract reports: H was observed to ameliorate IRI in the DCD liver by maintaining microcirculation, mitochondrial functions, and redox status, as well as suppressing the cytoplasmic…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model.
This animal study examined Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model. The abstract describes Porcine model. The abstract reports: The ratio of albumin stained to unstained areas was analyzed and found to be lower in the H group than in the other groups,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
BACKGROUND: Lung ischemia-reperfusion injury (LIRI) remains an important factor for the early mortality of lung transplantations. Hydrogen (H2) can attenuate lung injury and improve lung function in animal experiments. In previous studies, pulmonary microvascular endothelial cells (PMVECs) were used to simulate LIRI.
Read MoreHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
This animal study examined Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats. The abstract describes Rat model. The abstract reports: These results indicate that HCS treatment can improve cardiac function by reducing interstitial fibrosis in pressure‑overloaded rats through its anti‑oxidative properties and via suppression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
This uncontrolled human study examined Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. The abstract describes Human participants; sample size 83; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Treatment with hydrogen molecule attenuated cardiac dysfunction in streptozotocin-induced diabetic mice, which was independent of glycemic control. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInsufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model.
This uncontrolled human study examined Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model. The abstract describes Human participants. The abstract reports: We suggest that H₂ insufflation is a possible new potential therapy for counteracting CPB-induced systemic inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
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