Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension
This animal study examined Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension. The abstract describes Rat model. The abstract reports: A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H) improves blood pressure control in end-stage kidney disease. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice.
This animal study examined Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings identify that hydrogen-rich saline confers protection against fracture-caused chronic allodynia via spinal down-modulation of CXCL1-dependent TfR1-mediated iron accumulation in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.
This animal study examined Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease
This uncontrolled human study examined Effect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.
This animal study examined Hydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway. The abstract describes Mouse model. The abstract reports: We uncovered that hydrogen (H) could alleviate apoptosis response and ECM degradation in human chondrocytes via inhibiting the activation of the JNK signaling pathway.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen treatment reduces tendon adhesion and inflammatory response.
This animal study examined Hydrogen treatment reduces tendon adhesion and inflammatory response. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle.
This animal study examined Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS seems to be effective in attenuating IR injury in skeletal muscle via its antioxidant, anti-apoptosis, and anti-autophagy effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
This animal study examined Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide. The abstract describes Rat model. The abstract reports: These results imply that one of the functions of H2 exhibits cytoprotective effects and transcriptional alterations through reducing ONOO-. Moreover, novel pharmacological strategies aimed…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation.
This animal study examined Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation. The abstract describes Mouse model. The abstract reports: H2 markedly inhibited RANKL-induced activation, nuclear translocation, and transcriptional activity of NF-κB (P These results demonstrated that H2 could be an effective therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
This animal study examined Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast. The abstract describes Rat model. The abstract reports: Recently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
This animal study examined Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Obese rats, induced by a high-fat diet, showed a higher gingival level of 8-hydroxydeoxyguanosine and a lower level of alveolar bone density compared to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
This animal study examined Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress. The abstract describes Mouse model. The abstract reports: Rheumatoid arthritis (RA) is a chronic inflammatory disease which results in progressive destruction of the joint. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.
This animal study examined Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model.
This animal study examined Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A growing body of evidence suggests that hydrogen is a novel, selective antioxidant that exerts a protective effect against organ damage. This is an automated editorial draft based on the abstract and requires source review before publication.
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