Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion.
This animal study examined Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 30 min. The abstract reports: H(2) saline has an anti-inflammatory effect on rat hearts with regional myocardial I/R. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.
Ischemia or hypoxia‑induced myocardial injury is closely associated with oxidative stress. Scavenging free radicals and/or enhancing endogenous antioxidative defense systems may be beneficial for the impediment of myocardial ischemic injury. Hydrogen (H2) gas, as a water‑ and lipid‑soluble small molecule, is not only able to selectively eliminate hydroxyl (·OH) free radicals, but also to enhance endogenous antioxidative defense systems in rat lungs and arabidopsis plants.
Read MoreInhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
This in vitro or cellular study examined Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen-rich saline; reported duration 14 days. The abstract reports: This study suggests that topical application of H2 could protect CECs against corneal damage factors through anti-apoptotic effect, reduce the incidence and severity of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBreathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
This animal study examined Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart. The abstract describes Mouse model; reported duration 60 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
This animal study examined Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway. The abstract describes Mouse model. The abstract reports: We found that molecular hydrogen (H2) exerts an anti-inflammatory effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis.
This in vitro or cellular study examined Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis. The abstract describes Endothelial cell model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.
This animal study examined The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death. The abstract describes Animal model; sample size 5; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation during EVLP improved the function of DCD lungs, which may increase the utilization of DCD lungs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
This animal study examined Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HRS was demonstrated to attenuate CPB‑induced myocardial injury, suppress AQP‑1 and AQP‑4 expression following CPB treatment and protect myocardial cells via the PI3K/Akt signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports
This animal study examined Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports. The abstract describes Rabbit model. The abstract reports: ESR showed a significantly decreased signal magnitude, and fluorescence intensity by oxidized HPF was significantly less in the H2-dissolved solution. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
This animal study examined Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Protective effect of hydrogen (H(2)) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
This in vitro or cellular study examined Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
This animal study examined Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results showed a protective effect of HRS on pressure overload-induced cardiac hypertrophy in rats, which may be associated to a decreasing in JAK-STAT…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.
This in vitro or cellular study examined Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I. This is an automated editorial draft based on the abstract and requires source review before publication.
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