Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
This animal study examined Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It has previously been demonstrated that hyperglycemia‑induced oxidative stress and inflammation are closely associated with the development of diabetic complications, including diabetic neuropathy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
This uncontrolled human study examined Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These data demonstrated that HRS can improve survival rate, attenuate neuroinflammation, astrocyte and microglial activation, neuronal injury and mitochondrial dysfunction in juvenile SAE rat…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.
This animal study examined Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: These results suggested that H2 holds promise for the prevention of inflammation related to perinatal brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression.
This animal study examined PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression. The abstract describes Mouse model. The abstract reports: The results showed the expression of PPARα was decreased in SAE mice and that activation of PPARα in septic mice improved the survival rate…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImpact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet.
This animal study examined Impact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
This animal study examined Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Our results suggest that LPS-induced apoptosis, oxidative damage and inflammation in the fetal brain were ameliorated by maternal H2 administration. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.
This uncontrolled human study examined Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 40 min. The abstract reports: This observation demonstrated that hydrogen-rich saline peritoneal injection improves histologic and functional assessment in a rat model of CO encephalopathy. Hydrogen saline has potentials…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.
This uncontrolled human study examined Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro. The abstract describes Human participants. The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePerioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine.
This animal study examined Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats.
This animal study examined The neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Arterial oxygen partial pressure (PaO) and arterial oxygen saturation (SaO) results showed that HOS and HOHS could improve the oxygenation of the rats with…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice.
This animal study examined Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 7 days. The abstract reports: HRW improves sleep consolidation and increases neuronal activation in sleep-related brain regions. It may serve as a simple, effective treatment to improve recovery after…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation exerts anti-seizure effects by preventing oxidative stress and inflammation in the hippocampus in a rat model of kainic acid-induced seizures
This animal study examined Hydrogen inhalation exerts anti-seizure effects by preventing oxidative stress and inflammation in the hippocampus in a rat model of kainic acid-induced seizures. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 5 days. The abstract reports: Hydrogen gas (H) is an antioxidant with demonstrated neuroprotective efficacy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
This animal study examined Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTranscriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.
This animal study examined Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: H is identified as a potent agent against NEMP exposure-induced brain damage and has the potential to be a promising electromagnetic radiation protectant. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperbaric hydrogen therapy improves secondary brain injury after head trauma.
This animal study examined Hyperbaric hydrogen therapy improves secondary brain injury after head trauma. The abstract describes Mouse model; sample size 40; reported duration 90 minutes. The abstract reports: Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.
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