Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
This animal study examined Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We have demonstrated that hydrogen gas (H), a selective antioxidant, exerts protective effects in septic mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.
This in vitro or cellular study examined Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis. The abstract describes Lymphocyte cell model. The abstract reports: These results indicate that H(2) released from intestinal bacteria can suppress inflammation induced in liver by ConA. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIntake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver.
This animal study examined Intake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that intake of HRW had no significant effect on the activities of various cytochrome P450 (CYP) enzymes (CYP1A1, 1A2, 2B, 2C,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease.
This uncontrolled human study examined Nanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease. The abstract describes Human participants. The abstract reports: Moreover, hepatic transcriptome showed a reprogramed liver metabolism profile with reduced lipid synthesis and increased fatty acid metabolism. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water.
This animal study examined Hepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model
This animal study examined Effects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We hypothesized that the null result was due to low H concentrations. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
This animal study examined Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. The abstract describes Rat model. The abstract reports: The mechanism of this phenomenon suggests that H2 may have effectively attenuated AOC‑induced inflammatory and oxidative damage, and decreased matrix metalloproteinase activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
This animal study examined Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Storage of liver grafts in hydrogen-rich UW solution resulted in superior functional and morphologic protection against IRI via the up-regulation of HO-1 expression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.
This animal study examined Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice. The abstract describes Mouse model. The abstract reports: Therefore, the results of this study show that ERW can be proposed to protect the liver against CCl(4)-induced oxidative damage in mice, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
This animal study examined Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: Consumption of hydrogen-rich water may be an effective treatment for NASH by reducing hepatic oxidative stress, apoptosis, inflammation, and hepatocarcinogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection.
This animal study examined Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation; reported duration 120 minutes. The abstract reports: In this experimental study, we showed that inhaled hydrogen during major liver resection unquestionably reduced the level of oxidative stress associated with ischemia-reperfusion damage.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
This animal study examined Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: We found that H2 ameliorated H/R-induced cholangiocytes apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B.
This uncontrolled human study examined Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: HRW significantly attenuates oxidative stress in CHB patients, but further study with long-term treatment is required to confirm the effect of HRW on liver…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
This animal study examined Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. The abstract describes Mouse model. The abstract reports: It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
This animal study examined Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: HRW protects against chronic EtOH-induced liver injury, possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and…. This is an automated editorial draft based on the abstract and requires source review before publication.
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