Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-κB signaling pathway.
This animal study examined Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-κB signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 90 min. The abstract reports: Hydrogen has been demonstrated to function as a novel antioxidant and exert therapeutic antioxidant activity in a number of diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury.
This animal study examined Hyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HHOS has protective effects against liver injury in a rat model of HSR. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against liver injury in rats with obstructive jaundice.
This animal study examined Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice. The abstract describes Rat model; sample size 56; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress.
This animal study examined Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We observed that HRS visibly improved ischemia-reperfusion injury (IRI) by reducing various parameters of ERS stress as evidenced by down-regulation of the mRNA as…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3.
This animal study examined High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.
This animal study examined Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury. This effect may be mediated by both…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective role of hydrogen-rich saline in experimental liver injury in mice.
This animal study examined The protective role of hydrogen-rich saline in experimental liver injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could protect against liver injury and also inhibit the processes leading to liver cirrhosis and hepatocyte compensatory proliferation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs.
This animal study examined Influence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Intervention with hydrogen-rich saline could exert a protective effect against liver ischaemia-reperfusion combined resection injury through the reduction of oxidative stress and hepatocyte autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway
This animal study examined Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway. The abstract describes Mouse model; sample size 6. The abstract reports: Our findings indicate that HCH may protect the liver against I/R injury through the A dependent PI3K-Akt pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs.
This animal study examined Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS treatment significantly decreased serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBIL) activity and TUNEL-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver.
This animal study examined Hydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver. The abstract describes Rat model; reported duration 90 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of oral intake of hydrogen water on liver fibrogenesis in mice.
This animal study examined Effects of oral intake of hydrogen water on liver fibrogenesis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: We conclude that hydrogen water protects hepatocytes from injury by scavenging hydroxyl radicals and thereby suppresses liver fibrogenesis in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis.
This animal study examined Hydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The protective effect of HS can be attributed to ER stress and apoptosis inhibition. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats.
This animal study examined Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePossible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation
This observational study examined Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation. The abstract describes Human participants. The abstract reports: The data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H2 application…. This is an automated editorial draft based on the abstract and requires source review before publication.
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