Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.
This animal study examined Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: We find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the RNA sequencing and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTwo weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study.
This uncontrolled human study examined Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 4 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas represses the progression of lung cancer via down-regulating CD47.
This animal study examined Hydrogen gas represses the progression of lung cancer via down-regulating CD47. The abstract describes Mouse model. The abstract reports: In our previous study, our project group found that H2 could decrease the expression of CD47 in lung cancer A549 cells via the next-generation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
This animal study examined Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study extended our original analysis of the ability of hydrogen to stimulate NLRP3 inflammasome/GSDMD activation in pyroptosis and revealed possible mechanism (s) for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSuppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis.
This in vitro or cellular study examined Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis. The abstract describes A549 cell model. The abstract reports: Our previous study found that hydrogen gas (H) could efficiently inhibit lung cancer progression; however, the underlying mechanisms still remains to be elucidated. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis.
This uncontrolled human study examined Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis. The abstract describes Human participants; sample size 55; hydrogen delivered as hydrogen inhalation. The abstract reports: Exhausted cluster of differentiation (CD)8+ T cells lose immunological activity due to mitochondrial dysfunction caused by peroxisome proliferator‑activated receptor γ coactivator 1α (PGC‑1α) inactivation, resulting in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension
This animal study examined Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. The abstract describes Rat model. The abstract reports: Our findings suggest that chronic H gas inhalation may help prevent LV hypertrophy in hypertensive DS rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of oral hydrogen water as an antioxidant on pulmonary hypertension
This animal study examined Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the mean pulmonary arterial pressure, right ventricle weight and right ventricular hypertrophy index in MCT group were significant higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension.
This animal study examined The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: MPH resulted in a significantly increased number of MCs in both the pneumatic and respiratory parts of the lungs, an increased number of tryptase-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation
This animal study examined Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation. The abstract describes Rat model; reported duration 5 weeks. The abstract reports: We found that the systolic and diastolic blood pressure (BP) increased significantly in rats exposed to intermittent hypoxia, both of which were markedly attenuated…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats.
This animal study examined Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water (HW) has been suggested to possess antioxidant properties of value in treatments of lifestyle diseases and for prevention of latent pathologies. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.
This animal study examined Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results suggest that hydrogen-rich saline ameliorates the progression of pulmonary hypertension induced by monocrotaline in rats, which may be associated with its antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.
This uncontrolled human study examined Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
This animal study examined Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. The abstract describes Rat model. The abstract reports: Molecular hydrogen ameliorates MCT-induced PAH in rats by suppressing macrophage accumulation, reducing oxidative stress and modulating the STAT3/NFAT axis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes
This case report or case series examined Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes. The abstract describes Human participants. The abstract reports: This case study suggests that molecular hydrogen therapy may be a promising treatment for patients with SLE-PAH, particularly due to its immunomodulatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.
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