Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
This animal study examined Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast. The abstract describes Rat model. The abstract reports: Recently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
This animal study examined Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Obese rats, induced by a high-fat diet, showed a higher gingival level of 8-hydroxydeoxyguanosine and a lower level of alveolar bone density compared to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
This animal study examined Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress. The abstract describes Mouse model. The abstract reports: Rheumatoid arthritis (RA) is a chronic inflammatory disease which results in progressive destruction of the joint. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.
This animal study examined Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model.
This animal study examined Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A growing body of evidence suggests that hydrogen is a novel, selective antioxidant that exerts a protective effect against organ damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation
This case report or case series examined Molecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation. The abstract describes Human participants. The abstract reports: This is the first case report to highlight severe MTX-induced myelosuppression in an RA patient and to demonstrate the potential of molecular hydrogen therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen water consumption prevents osteopenia in ovariectomized rats.
This animal study examined Hydrogen water consumption prevents osteopenia in ovariectomized rats. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 3 months. The abstract reports: HW consumption prevents osteopenia in ovariectomized rats possibly through the ablation of oxidative stress induced by oestrogen withdrawal. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses activated Wnt/β-catenin signaling.
This animal study examined Molecular hydrogen suppresses activated Wnt/β-catenin signaling. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We found that H2 suppresses activated Wnt/β-catenin signaling by promoting phosphorylation and degradation οf β-catenin. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis
This animal study examined Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 30 min. The abstract reports: RESULTS The antioxidant effects of HW suppressed oxidative damage, which may have aided the inhibition of ECM-degrading enzymes (MMP3, MMP13, ADAMT4, and ADAMT5), the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
This animal study examined Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 6 weeks. The abstract reports: Treatment with molecular hydrogen alleviates microgravity-induced bone loss in rats. Molecular hydrogen could thus be envisaged as a nutritional countermeasure for spaceflight but remains…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease
This animal study examined RETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease. The abstract describes Rat model; sample size 18; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 10 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
This in vitro or cellular study examined Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?. The abstract describes Cell culture / in vitro model. The abstract reports: Recent studies in animal models of focal or global cerebral ischemia and cerebral ischemia in humans suggest that hydrogen has pleiotropic neuroprotective properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.
This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress.
This animal study examined Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress. The abstract describes Rat model; sample size 84; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 14 days. This is an automated editorial draft based on the abstract and requires source review before publication.
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