Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial.
This study protocol examined Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; sample size 450; hydrogen delivered as injected or infused hydrogen. The abstract reports: Recent accumulating evidence has suggested that early brain injury is also involved in the development of delayed cerebral ischemia, and that hydrogen can prevent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway.
This in vitro or cellular study examined Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could attenuate neuronal apoptosis in EBI and improve the neurofunctional outcome after SAH, partially via the Akt/GSK3β pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury.
This animal study examined Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury. The abstract describes Rat model; sample size 60; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrated that H2 significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEfficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
This study protocol examined Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management
This animal study examined Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation was beneficial when begun after ROSC, even when delivered in the absence of hyperoxia. Combined TTM and H2 inhalation was more effective…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSkin ulcers infected with conditional pathogenic strains treated with local hydrogen water packing in two pemphigus vulgaris patients: Case reports with follow‐up for 2 months
This case report or case series examined Skin ulcers infected with conditional pathogenic strains treated with local hydrogen water packing in two pemphigus vulgaris patients: Case reports with follow‐up for 2 months. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro.
This uncontrolled human study examined Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: HW intake via TF was demonstrated, for severely hospitalized elderly patients with PU, to execute wound size reduction and early recovery, which potently ensue…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment
This in vitro or cellular study examined Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. The abstract describes Fibroblast model; hydrogen delivered as hydrogen water. The abstract reports: Extract from HW-treated HGF cells scavenged ROO· more markedly than that from DDW-treated cells, suggesting that HW can increase the intracellular antioxidant capacity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.
This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level
This uncontrolled human study examined A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level. The abstract describes Human participants; sample size 10; reported duration 30 min. The abstract reports: H2 inhalation of at least 3% concentration for 30 min delivered enough HC, equivalent to the animal experiment levels, in the blood without compromising…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA Systematic Review of Molecular Hydrogen Therapy in Cancer Management.
This systematic review examined A Systematic Review of Molecular Hydrogen Therapy in Cancer Management. The abstract describes Published literature review. The abstract reports: From our analysis, H2 plays a promising therapeutic role as an independent therapy as well as an adjuvant in combination therapy, resulting in an…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.
This animal study examined Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 12 weeks. The abstract reports: ELISA assay showed hydrogen-rich saline lowered the levels of pro-inflammatory cytokines (IL-8 and IL-6) and anti-inflammatory cytokine IL-10 in bronchoalveolar lavage fluid and serum…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA narrative review of hydrogen therapy for COPD: aging-related insights.
This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.
This animal study examined Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
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