Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined however, many reports on therapeutic applications of H₂ have the limitation to regard H₂ only as a scavenger for the hydroxyl radical and peroxynitrite. H₂ is proposed to convert the quinone intermediates to the fully reduced ubiquinol, thereby…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Studies have shown that H₂ inhalation has the therapeutic effects in many animal studies and clinical trials, and its application…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Further, H₂ is easy to use and has neuroprotective effects with no major side-effects, indicating that H₂ administration is a…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Although the administration of molecular hydrogen (H₂, dihydrogen) has been recognized as an effective innovative therapeutic procedure in biomedicine, H₂…
Read ArticleIn In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a sin,…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. mibyou cannot be detected nor treated by modern medicine, H₂ is able to suppress the pathogenesis of pre-symptomatic diseases, and…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The authors provide elegant kinetic evidence demonstrating that H₂ exposure induces a near-immediate reduction in Complex III activity, followed by…
Read ArticleThe researchers observed that H₂ induces the mitochondrial unfolded protein response (UPRmt) in cultured cells exposed to H₂ and in mouse liver after H₂ water administration. The authors…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen (H₂), administered primarily as hydrogen-rich water (HRW), has emerged as a potential therapeutic candidate due to its selective…
Read ArticleIn conclusion, hydrogen molecule may be neuroprotective against ALS, possibly through abating oxidative and nitrosative stress and preserving mitochondrial function. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, spinal cord neurons were preserved by hydrogen administration after mechanical injury in a dose-dependent manner. These results are preclinical and suggest molecular hydrogen's therapeutic potential in…
Read ArticleThe researchers found that the expression of LC3 was increased after OGD/R which can be further enhanced by H₂ and RAP treatment, but treatment with 3-MA was opposite.…
Read ArticleIn rats, after the HRW treatment, the oxidative stress status in the liver was improved, SOD activities and MDA levels were restored, CAT activities and GSH levels were…
Read ArticleIn mice, the removal of mtROS by H₂ reduced the generation of oxidized mitochondrial DNA and consequently decreased its binding to NLRP3, thereby inhibiting the NLRP3 inflammasome activation.…
Read ArticleIn 0 patients with progressive muscular dystrophy (PMD), less prominent effects with the double-blind trial compared to the open-label trial were likely due to a lower amount of…
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