Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In GC-1 spermatogonial cells and TM-3 Leydig cells, two well-established male reproductive cell lines, were exposed to NEMP, specifically, molecular hydrogen reduced the production of ROS and restored mitochondrial function, thereby alleviating oxidative stress and apoptosis. These findings from a laboratory model…
Read ArticleIn rats, hRS treatment had no significant effect on blood pressure, but it effectively attenuated left ventricular hypertrophy in SHR. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleIn Here, the researchers investigated the effect of H₂ on mitochondria in cultured human neuroblastoma SH-SY5Y cells, pretreatment of cells with 50% H₂ gas for 18 h in…
Read ArticleIn a laboratory model, as a result, H₂ protected the cultured cells against the cytotoxic effects induced by tert-butyl hydroperoxide; H₂ suppressed cellular fatty acid peroxidation and cell…
Read ArticleIn a laboratory model, an appropriate volume fraction of H₂ significantly decreased mitochondrial reactive oxygen species (ROS) levels, increased the number of mitochondria, and promoted mitophagy, thus enhancing…
Read ArticleIn rats, HRW treatment decreased DAPI/PI/β‐PDGFR and β‐PDGFR/ROS‐positive cells while increasing the β‐PDGFR/SOD‐positive cells, indicating that HRW attenuated HI‐induced oxidative stress injury in pericytes (Figure 1B–D ). These…
Read ArticleIn rats, eLISA analysis showed decreased TNF-α and IL-1β and increased IL-10 expression levels in the hydrogen-rich saline-treated group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, the present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex I activity)…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The threshold shifts in animals given GeO 2 and hydrogen water showed approximately 20–30 threshold shifts at all frequencies, which…
Read ArticleThis narrative review examined the available evidence on molecular hydrogen. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline treatment significantly improved the amount of surviving cells (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn male C57BL/6 mice, treatment with HS reduced the levels of these markers and alleviated morphological defects in the mitochondria following injury. These preclinical findings add evidence supporting…
Read ArticleIn a laboratory model, H₂ solely reduced mitochondrial membrane potential of the cultured cells by 11.3% as assessed by TMRE. These findings from a laboratory model add evidence…
Read ArticleIn rats, however, it is unclear whether H₂ affects gene expression directly or through indirect effects as a consequence of health improvement. These preclinical findings add evidence supporting…
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