Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
Read ArticleIn a laboratory model, initially found that H₂ reduced intracellular ROS accumulation and malondialdehyde levels in both vitiligo specimens and hydrogen peroxide-treated melanocytes in vitro in a concentration-…
Read ArticleIn 10 participants, H₂ significantly augmented breath acetone and enhanced oxygen uptake during exercise (P < 0.01). These findings add human evidence that helps define the outcomes that…
Read ArticleIn a laboratory model, mechanistically, released H₂ assists chemotherapeutic drug to efficiently inhibit cancer metastasis by immunoactivating intratumoral M1-phenotype macrophages and consequently downregulating the expression of metastasis-related matrix…
Read ArticleIn a complete Freund's Adjuvant-induced RA mouse model, this controlled hydrogen release behavior significantly downregulated pro-inflammatory mediators, protecting chondrocytes from apoptosis and preventing cartilage degradation. These preclinical findings…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Pre-treatment with H₂ is more effective than post-treatment [ 66 ]. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. The reviewed…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn a laboratory model, H₂ treatment significantly improved the rate of forward motility, whereas treatment with nitrogen gas did not. The authors concluded that the results illustrated that…
Read ArticleIn The researchers found that treatment with H₂ prevented RANKL-induced osteoclast differentiation in RAW264.7 cells and BMMs, treatment with H₂ decreased intracellular reactive oxygen species (ROS) formation, suppressed…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In recent years, several studies have provided preliminary evidence for the protective effects of hydrogen on spinal cord injury (SCI).…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThis systematic review examined the available molecular-hydrogen literature. Preclinical studies of these showed some benefit but were inconclusive in models of global brain injury involving systemic ischemia. The…
Read ArticleMolecular hydrogen gas (HG), administered through inhalation or as hydrogen-rich fluids (HRF), has demonstrated antioxidant, anti-inflammatory, antiapoptotic, cytoprotective, and beneficial mitochondrial effects in critical illness. This source-grounded publication…
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