Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.

This animal study examined Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress. The abstract describes Rabbit model. The abstract reports: Results show that irrigation of the damaged eyes with H solution immediately after the injury and then within next five days renewed corneal transparency…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

This randomized controlled trial examined Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. The abstract describes Human participants; sample size 73. The abstract reports: H2-water may have a potential for suppressing dementia in an oxidative stress model and in the APOE4 carriers with MCI. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model

This animal study examined Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: Histological examinations showed pyknotic neuronal morphologies and elevated reactive oxygen species (ROS) in the VaD hippocampus, whereas H administration mitigated these alterations. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway

This animal study examined Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway. The abstract describes Mouse model. The abstract reports: We found that H can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis.

This uncontrolled human study examined Hydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease, a neurodegenerative disorder characterized by sporadic and progressive degenerative loss of cell bodies of both…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.

This uncontrolled human study examined Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Sepsis is associated with numerous physiological and biochemical abnormalities that result in a life-threatening condition. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review.

This narrative review examined Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review. The abstract describes Published literature review. The abstract reports: Therefore, we conducted a literature review on the mechanism by which H improves acute and chronic fatigue in animals and healthy people and showed…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.

This narrative review examined Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity. The abstract describes Published literature review. The abstract reports: Excessive levels of both pro- and anti-oxidant species qualify as oxidative stress (OS) and result in damage to molecules and cells. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration

This animal study examined The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: H inhalation could alleviate CNV leakage in a laser-induced mouse CNV model, and the potential mechanism might be related to the suppression of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats

This animal study examined A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. The abstract describes Rat model. The abstract reports: In this paper, we demonstrated that consumption of H-rich water (HRW) resulted in stimulated rat cardiac mitochondrial electron respiratory chain function and increased levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension.

This animal study examined Molecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: No differences in HR response to PE administration were found between any of the experimental groups. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway.

This animal study examined Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS was found to mitigate cardiac hypertrophy induced by pressure overload in rats and reduce atrial fibrosis and AF which was possibly achieved via…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway.

This animal study examined Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results confirmed the protection of HRS in LPS-induced ALI by regulating apoptosis through inhibiting the mTOR/TFEB signaling pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy.

This animal study examined Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results demonstrated that treatment with hydrogen improved the myocardial infarction size of hearts, cardiac function, apoptosis and cytokine release following MI/R in rats. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model

This animal study examined Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…. This is an automated editorial draft based on the abstract and requires source review before publication.

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