High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway.
This animal study examined High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway. The abstract describes Mouse model; sample size 6. The abstract reports: HCH resulted in the phosphorylation of Akt1 but not Akt2, and Akt1 inhibition markedly abolished HCH-induced cardioprotection. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as an Adjuvant Therapy in Severe Lupus Serositis With Heart Failure: A Case Report on Immune Modulation and Fatigue Reduction
This case report or case series examined Molecular Hydrogen as an Adjuvant Therapy in Severe Lupus Serositis With Heart Failure: A Case Report on Immune Modulation and Fatigue Reduction. The abstract describes Human participants. The abstract reports: This case highlights the potential of molecular hydrogen therapy as an adjuvant treatment in SLE, with observed benefits in immune modulation and fatigue reduction.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.
This uncontrolled human study examined Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Hydrogen exerts protective effect against SIC, which may be achieved through the promotion of autophagy and mitophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression
This uncontrolled human study examined Hydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression. The abstract describes Human participants. The abstract reports: It has been showed that the change of mitochondrial dynamics has been proved to be one of the main causes of death in patients…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress.
This animal study examined Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Cardiac hypertrophy occurs as a result of high levels of thyroid hormone, which may contribute to heart failure and is closely related to oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen as adjuvant treatment for unstable angina
This uncontrolled human study examined Effects of hydrogen as adjuvant treatment for unstable angina. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Clinical analysis showed hydrogen-rich water intake relieved angina symptoms in unstable angina patients. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice.
This animal study examined Protective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePeripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial.
This randomized controlled trial examined Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial. The abstract describes Human participants; sample size 34; hydrogen delivered as hydrogen water. The abstract reports: Daily consumption of high H2 water improved the endothelial function of the arteries or arterioles assessed by the PAT test. The results suggest that…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress.
This narrative review examined A New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Redox dysregulation and a dyshomeostasis of inflammation arise from, and result in, cellular aberrations and pathological conditions, which lead to cardiovascular diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells
This animal study examined H2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside.
This narrative review examined Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model.
This animal study examined Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model. The abstract describes Porcine model. The abstract reports: The ratio of albumin stained to unstained areas was analyzed and found to be lower in the H group than in the other groups,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
This in vitro or cellular study examined The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. The abstract describes Endothelial cell model; reported duration 4 hours. The abstract reports: Hydrogen-attenuated inflammatory response in a PMVECs lung transplantation model during cold storage. The effect may be achieved by inhibition of p38 MAPK and NF-κB…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
This animal study examined Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats. The abstract describes Rat model. The abstract reports: These results indicate that HCS treatment can improve cardiac function by reducing interstitial fibrosis in pressure‑overloaded rats through its anti‑oxidative properties and via suppression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
This uncontrolled human study examined Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. The abstract describes Human participants; sample size 83; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Treatment with hydrogen molecule attenuated cardiac dysfunction in streptozotocin-induced diabetic mice, which was independent of glycemic control. This is an automated editorial draft based on the abstract and requires source review before publication.
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