Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.

This randomized controlled trial examined Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: In conclusion, these results suggest that supplementation with hydrogen-rich water may have a beneficial role in prevention of T2DM and insulin resistance. This is an automated editorial draft based on the abstract and requires source review before publication.

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Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial.

This randomized controlled trial examined Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial. The abstract describes Human participants; sample size 50; hydrogen delivered as hydrogen water. The abstract reports: There were no significant effect of EHW in the change in HOMA-IR in this study; larger-scale and longer-term study are needed to verify the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Health Effects of Electrolyzed Hydrogen Water for the Metabolic Syndrome and Pre-Metabolic Syndrome: A 3-Month Randomized Controlled Trial and Subsequent Analyses.

This randomized controlled trial examined Health Effects of Electrolyzed Hydrogen Water for the Metabolic Syndrome and Pre-Metabolic Syndrome: A 3-Month Randomized Controlled Trial and Subsequent Analyses. The abstract describes Human participants; sample size 181; hydrogen delivered as hydrogen water; reported duration 3 months. The abstract reports: Among the group that drank EHW for 3 months, those who also engaged in a high level of physical activity showed a significant difference…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study.

This randomized controlled trial examined Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: H slightly improved metabolic abnormalities and gut microbiota dysbiosis, providing a novel target and theoretical basis for the prevention and treatment of blood glucose…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial.

This randomized controlled trial examined Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial. The abstract describes Human participants; reported duration 14 days. The abstract reports: However, no significant differences were found between groups ( > 0.05). : Administration of hydrogen-rich jelly for 14 days decreased gingival inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

This randomized controlled trial examined Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. The abstract describes Human participants; sample size 73. The abstract reports: H2-water may have a potential for suppressing dementia in an oxidative stress model and in the APOE4 carriers with MCI. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water and heart rate variability biofeedback as treatments for chronic fatigue syndrome: a pilot randomized trial

This registered clinical trial examined Hydrogen water and heart rate variability biofeedback as treatments for chronic fatigue syndrome: a pilot randomized trial. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen water. The abstract reports: All participant activities were completed in their homes.Intervention: Two daily treatments were self-administered by participants: 2–3 glasses of hydrogen-producing drinking water and/or heart rate…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial.

This randomized controlled trial examined Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial. The abstract describes Human participants; sample size 34; hydrogen delivered as hydrogen water. The abstract reports: Daily consumption of high H2 water improved the endothelial function of the arteries or arterioles assessed by the PAT test. The results suggest that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function

This uncontrolled human study examined Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: H2 may protect the vasculature from shear stress-derived detrimental ROS, such as the hydroxyl radical, by maintaining the nitric oxide-mediated vasomotor response. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.

This randomized controlled trial examined Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 6 weeks. The abstract reports: Daily consumption of hydrogen-rich water is a potentially novel, therapeutic strategy for improving QOL after radiation exposure. Consumption of hydrogen-rich water reduces the biological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.

This randomized controlled trial examined Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy. The abstract describes Human participants; sample size 80; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study

This randomized controlled trial examined Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Assessments were conducted at baseline (T0) and on Days 1 (T1), 3 (T2), 7 (T3), and 14 (T4) post-treatment.ResultsThe HW group showed significant OM…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma: a single-center, randomized controlled study.

This single-center randomized controlled trial evaluated perioperative hydrogen/oxygen inhalation in adults undergoing first-time glioma surgery. Eighty-nine patients were randomized and 75 were included in the per-protocol analysis (38 hydrogen/oxygen and 37 oxygen control). The intervention group inhaled 66.7% hydrogen and 33.3% oxygen by nasal cannula for more than 2 hours daily from admission through discharge; the control group received 33.3% oxygen. Serial CT measurements showed lower brain-edema volume and greater edema regression before discharge in the hydrogen group. Selected sleep and pain measures improved, while inflammatory markers, hospital and ICU stay, and recorded complications did not differ significantly between groups.

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Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study.

This uncontrolled human study examined Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 4 hours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis.

This uncontrolled human study examined Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis. The abstract describes Human participants; sample size 55; hydrogen delivered as hydrogen inhalation. The abstract reports: Exhausted cluster of differentiation (CD)8+ T cells lose immunological activity due to mitochondrial dysfunction caused by peroxisome proliferator‑activated receptor γ coactivator 1α (PGC‑1α) inactivation, resulting in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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