Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression.
This animal study examined Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline; reported duration 28 day. The abstract reports: Histological data showed that the HRS treatment significantly decreased the fibrosis in renal tissues when compared with the IR group, and both of BUN…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats.
This animal study examined Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats. The abstract describes Rat model. The abstract reports: Results: One day after the injection, serum levels of urea nitrogen were significantly lower in H gas-inhaling CIAKI rats (17.6 ± 2.3 mg/dl) than…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.
This uncontrolled human study examined Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients. The abstract describes Human participants. The abstract reports: However, the mean proportion of reversibly oxidized albumin in outlet serum was significantly lower than that in inlet serum following the H2-HD session, whereas…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNovel haemodialysis (HD) treatment employing molecular hydrogen (H)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study.
Recent studies have revealed unique biological characteristics of molecular hydrogen (H) as an anti-inflammatory agent. We developed a novel haemodialysis (E-HD) system delivering an H (30-80 ppb)-enriched dialysis solution by water electrolysis, and conducted a non-randomized, non-blinded, prospective observational study exploring its clinical impact. Prevalent chronic HD patients were allocated to either the E-HD (n = 161) group or the conventional HD (C-HD: n = 148) group, and received the respective HD treatments during the study.
Read MoreHydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model.
This in vitro or cellular study examined Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreApplication of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment-Perspective View.
This uncontrolled human study examined Application of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment-Perspective View. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury
This animal study examined Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: After 72 hours of glycerol injection (8 mL/kg), we found that glycerol triggered oxidative stress, inflammatory reactions, and apoptotic events. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreQuantification of dissolved H and continuous monitoring of hydrogen-rich water for haemodialysis applications: An experimental study.
This uncontrolled human study examined Quantification of dissolved H and continuous monitoring of hydrogen-rich water for haemodialysis applications: An experimental study. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.
This animal study examined Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: We found that CsA increased the levels of reactive oxygen species (ROS) and malonaldehyde (MDA), but it reduced glutathione (GSH) and superoxide dismutase (SOD)…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis.
This animal study examined Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water in a rat model of polycystic kidney disease
This observational study examined Effects of hydrogen-rich water in a rat model of polycystic kidney disease. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: This experiment showed that the effect of drinking large volumes of hydrogen-rich water was not significantly different from that of normal water, in terms…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen and kidney diseases: a scoping review based on scientometry and data analytics.
Acute kidney injury and chronic kidney disease impose substantial burdens on healthcare systems worldwide. Molecular hydrogen (H2) has emerged as a potential therapy due to its selective antioxidant, anti-inflammatory, and antiapoptotic properties. The present study reviews evidence on H₂-based renal interventions, examining therapeutic mechanisms, bibliometric trends, and existing research gaps based on data analytics.
Read MoreImmunomodulatory Effects of Molecular Hydrogen Therapy in Systemic Lupus Erythematosus With Pericarditis and Pleuritis: A Case Report
This case report or case series examined Immunomodulatory Effects of Molecular Hydrogen Therapy in Systemic Lupus Erythematosus With Pericarditis and Pleuritis: A Case Report. The abstract describes Human participants. The abstract reports: Molecular hydrogen therapy had potential to modulate immune markers in this case study. Further investigation into its clinical efficacy and safety is necessary for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report.
Progressive fibrosing interstitial lung disease (PF-ILD) refers to a group of chronic lung conditions commonly associated with immunoglobulin G4-related disorders. It is characterized by progressive scarring (fibrosis) within the pulmonary interstitium, resulting in respiratory failure and early mortality. Some patients do not respond to standard therapeutic interventions.
Read MoreHydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis.
This animal study examined Hydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Increasing evidence suggests that environmental stress may disrupt gut microbial balance and promote inflammation that leads to distant organs, including cochlea. This is an automated editorial draft based on the abstract and requires source review before publication.
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