Protective effects of molecular hydrogen on lung injury from lung transplantation
This narrative review examined Protective effects of molecular hydrogen on lung injury from lung transplantation. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The reviewed studies showed that H improved the outcomes of lung transplantation by decreasing oxidative stress and inflammation at the donor and recipient phases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is a potential protective agent in the management of acute lung injury.
This uncontrolled human study examined Molecular hydrogen is a potential protective agent in the management of acute lung injury. The abstract describes Human participants. The abstract reports: Several studies have demonstrated the preventive and therapeutic effects of molecular hydrogen in the various diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline protects the lung against oxygen toxicity.
This animal study examined Saturated hydrogen saline protects the lung against oxygen toxicity. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: The light microscope findings showed that saturated hydrogen saline reduced the impairment when compared with the saline group: Saturated hydrogen saline decreased lung edema,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
This uncontrolled human study examined Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated that inhaled hydrogen reduced transplant-induced lung injury and induced heme oxygenase (HO)-1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImmersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury.
This animal study examined Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. The abstract describes Rat model; sample size 3; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Immersing lungs in hydrogen-rich saline delivered hydrogen into the lung and consequently attenuated lung IRI. Hydrogen-rich solution appears to be a promising approach to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreItraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: Functional enrichment analysis showed that H2-related differential proteins could be related to muscle contraction, oxygen transport, protein synthesis, collagen barrier membranes, cell adhesion, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation.
This animal study examined Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated the inhalation of hydrogen gas, a novel medical therapeutic gas, ameliorates ventilator-induced lung injury (VILI); however, the molecular mechanisms by which…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses.
This animal study examined Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses. The abstract describes Mouse model. The abstract reports: We found that H/R-induced injury in our mouse model was associated with production of hydroxyl radicals as well as increased levels of colony-stimulating factors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline treatment on polymicrobial sepsis.
This animal study examined Effects of hydrogen-rich saline treatment on polymicrobial sepsis. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS has potential protective effects against sepsis by decreasing proinflammatory responses, oxidative stress, and apoptosis in a rat model of polymicrobial sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline provides protection against hyperoxic lung injury.
This animal study examined Hydrogen-rich saline provides protection against hyperoxic lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results of this study demonstrate that hydrogen-rich saline ameliorated hyperoxia-induced acute lung injury by reducing oxidative stress and inflammatory cascades in lung tissue. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics.
This animal study examined Protective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics. The abstract describes Mouse model. The abstract reports: Therapy with 2% H increased PaO/FiO ratios, MMP and ATP levels, RCR, complex I activity and MFN2 expression but decreased histological score and Drp1…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline ameliorates lipopolysaccharide-induced acute lung injury by reducing excessive autophagy.
This narrative review examined Saturated hydrogen saline ameliorates lipopolysaccharide-induced acute lung injury by reducing excessive autophagy. The abstract describes Published literature review; hydrogen delivered as hydrogen-rich saline. The abstract reports: In turn, autophagy is associated with inflammatory diseases and organ dysfunction, and studies have demonstrated that LPS treatment may trigger autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.
This animal study examined Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen, administered through inhalation, may exert potent therapeutic effects against ALI induced by HS/R and attenuate the activation of inflammatory cascades. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline attenuates endotoxin-induced lung dysfunction.
This animal study examined Saturated hydrogen saline attenuates endotoxin-induced lung dysfunction. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: If not controlled, excessive autophagy responses can result in cell death. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis.
This uncontrolled human study examined Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: RESULTS Mice exhibited increases in collagen deposition, hydroxyproline, type I collagen contents, and TGF-β1 production in lung tissues after LPS treatment. This is an automated editorial draft based on the abstract and requires source review before publication.
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