Hydrogen gas therapy: A promising approach for sepsis management post-burn injury by modulating inflammation, oxidative stress, and wound healing.
This uncontrolled human study examined Hydrogen gas therapy: A promising approach for sepsis management post-burn injury by modulating inflammation, oxidative stress, and wound healing. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Wound healing was monitored, with wound contraction rates recorded and histological assessments conducted using hematoxylin and eosin and Masson's trichrome staining to evaluate tissue…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping.
This uncontrolled human study examined Molecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Although the patient ultimately succumbed to irreversible chronic comorbidities on day 86, this case of severe tricuspid regurgitation and Child-Pugh class B alcoholic cirrhosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex promoting HO-1 expression.
This uncontrolled human study examined Hydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex promoting HO-1 expression. The abstract describes Human participants. The abstract reports: Hydrogen improved cell injury and mitochondrial quality, which were associated with HO-1 expression promoted by the Nrf2/YY1 complex in vitro. Thus, hydrogen treatment may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRecent Advances in Studies of Molecular Hydrogen against Sepsis.
This narrative review examined Recent Advances in Studies of Molecular Hydrogen against Sepsis. The abstract describes Published literature review. The abstract reports: Molecular hydrogen is a new type of antioxidant with strong free radical scavenging ability, which has been demonstrated to be effective for treating various…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreiTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: A total of 199 differential proteins were related with H in the intestinal protection of sepsis. H-related differential proteins were notably enriched in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePromising novel therapy with hydrogen gas for emergency and critical care medicine.
This narrative review examined Promising novel therapy with hydrogen gas for emergency and critical care medicine. The abstract describes Published literature review. The abstract reports: Studies undertaken by the Center have suggested possible therapeutic effects of hydrogen gas in relation to various aspects of emergency and critical care medicine,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
This in vitro or cellular study examined Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intraperitoneal administration of H2-rich saline resulted in large increases in H2 concentration in the IVC ranging from 0.00183 mg/L (0.114%) to 0.00725 mg/L (0.453%). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: a therapeutic antioxidant and beyond.
This uncontrolled human study examined Molecular hydrogen: a therapeutic antioxidant and beyond. The abstract describes Human participants. The abstract reports: Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.
This uncontrolled human study examined Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen is effective in relieving the gastric injury induced by aspirin-HCl, and the inhibitory effect is dose-dependent. The reason behind this may be that…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of a single inhalation of hydrogen gas in pigs.
This animal study examined Pharmacokinetics of a single inhalation of hydrogen gas in pigs. The abstract describes Animal model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBiological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity
This animal study examined Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. The abstract describes Rat model; reported duration 28 days. The abstract reports: Hydrogen-dissolved water has been suggested to be effective for alleviating the oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFeasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
This uncontrolled human study examined Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study. The abstract describes Human participants; sample size 107; hydrogen delivered as hydrogen inhalation. The abstract reports: HI in combination with TTM is a feasible therapy for patients with PCAS. (Circ J 2016; 80: 1870-1873). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
This animal study examined Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings suggest that hydrogen-rich saline reduces airway inflammation and remodeling in OVA-exposed mice by inhibiting NF-κB. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China
This observational study examined Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 24 week. The abstract reports: The HI therapy is related to significant amelioration in BP levels with acceptable safety profile in Chinese hypertensive adults after 24 weeks of treatment,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs.
This animal study examined Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
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