Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.

This animal study examined Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress. The abstract describes Rat model; sample size 30; reported duration 3 hours. The abstract reports: Inhalation of hydrogen gas could attenuate cognitive impairment in the ischemic rats. This protection is associated with decreased neuronal death in CA1 region and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model

This animal study examined Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: The HI group (n = 10) showed a transient increase in SV and CO followed by a decline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury.

This animal study examined Hydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen, which is a slight and specific cytotoxic oxygen radical scavenger, has been demonstrated to ameliorate early brain injury (EBI) through reactive oxygen species…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage

This animal study examined Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results of this study demonstrate that hydrogen-rich saline improves neurological outcomes in mice and reduces neuronal death by protecting against neural autophagy and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model.

This in vitro or cellular study examined Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model. The abstract describes Artificial skin model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study demonstrated that photoaging-related transcriptomic changes were detectable in artificial skin under a relatively low UVA dose (7 J/cm/day; total 21 J/cm) with minimal histological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

This animal study examined Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy. The abstract describes Animal model. The abstract reports: In vitro results showed that PDA@ZIF-8@AB nanoparticles can release H continuously for up to 5 days in an acidic microenvironment, while the photothermal properties…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition.

This in vitro or cellular study examined Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition. The abstract describes Epithelial cell model. The abstract reports: We have discovered a novel pattern of wound healing induced by molecular hydrogen treatment. This is the first time to reveal the direct link between…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells.

This in vitro or cellular study examined Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells. The abstract describes HaCaT keratinocyte model. The abstract reports: All of the results indicated that hydrogen decreased the levels of reactive oxygen species, 8‑iso‑prostaglandin F2α and malondialdehyde, and promoted the UVB exposure‑induced expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo.

This animal study examined Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo. The abstract describes Animal model. The abstract reports: We found that H(H2O)m prevented UV-induced ROS generation and inhibited UV-induced MMP-1, COX-2 and IL-6 expressions, and UV-induced JNK and c-Jun phosphorylation in HaCaT…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway.

This animal study examined Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that hydrogen-rich saline could ameliorate ischemia/reperfusion injury and improve flap survival rate by inhibiting the apoptosis factor and, at the same…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment

This in vitro or cellular study examined Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. The abstract describes Fibroblast model; hydrogen delivered as hydrogen water. The abstract reports: Extract from HW-treated HGF cells scavenged ROO· more markedly than that from DDW-treated cells, suggesting that HW can increase the intracellular antioxidant capacity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.

This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC  and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture

This uncontrolled human study examined Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture. The abstract describes Human participants; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Daily 10 min HW (dissolved hydrogen: 338–682 μg/mL, 41 °C) bathing and skin poultice with HW-impregnated towels for 11–98 days were demonstrated to improve…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.

This uncontrolled human study examined Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Although porphyrin levels showed a trend toward reduction, this change was not statistically significant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway

This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.

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