Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In Neuronal degeneration within hippocampal Cornu Ammonis 1 (CA1) regions was examined by Fluoro-Jade staining ex vivo, both hydrogen gas treatment regimens significantly improved spatial learning function and attenuated neuronal degeneration within hippocampal CA1 regions at 18 days post-resuscitation. These findings come…
Read ArticleIn 5 patients, oxidative stress was reduced and cytokine levels were unchanged in cardiogenic patients, whereas oxidative stress was unchanged and cytokine levels were diminished in the septic…
Read ArticleIn a laboratory model, hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx.…
Read ArticleIn 72 patients with outcome data, however, hydrogen + TTM32-TTM34 did not improve survival compared with TTM32-TTM34 alone (adjusted hazard ratio: 0.22 [95% CI, 0.05-1.06], p = 0.06).…
Read ArticleIn rats, the beneficial effects of hydrogen-rich saline were associated with decreased levels of oxidative products, as well as the increased levels of antioxidant enzymes. These preclinical findings…
Read ArticleIn this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. These preclinical findings add…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleThe researchers found that the beneficial effects of hydrogen-rich saline treatment were associated with decreased levels of oxidative products (8-iso-prostaglandin F2α and malondialdehyde) and inflammatory cytokines (tumor necrosis…
Read ArticleIn rabbits, no significant difference was observed between the two CA groups treated with different doses of H₂. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, the Kaplan-Meier analysis showed that H₂ significantly improved the 4 h-survival endpoint (log-rank P = 0.025 vs. placebo). These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, neuronal degeneration and microglial activation in a vulnerable brain region was suppressed by both TTM alone and H₂ inhalation alone, with the combined therapy of TTM…
Read ArticleIn an animal model, after the CPR, blood pH, base excess, and lactate showed significantly smaller deterioration in the hydrogen group than in the control group. These preclinical…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn rats, of this preclinical study suggest that water electrolysis-derived 60% hydrogen gas may improve short-term outcomes in cardiogenic global brain hypoxia-ischemia. These preclinical findings add evidence supporting…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. It has been reported that hydrogen gas exerts a therapeutic effect in a wide range of disease conditions, from acute…
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