Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
This uncontrolled human study examined Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. The abstract describes Human participants; sample size 83; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Treatment with hydrogen molecule attenuated cardiac dysfunction in streptozotocin-induced diabetic mice, which was independent of glycemic control. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion.
This animal study examined Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 30 min. The abstract reports: H(2) saline has an anti-inflammatory effect on rat hearts with regional myocardial I/R. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.
This animal study examined Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway. The abstract describes Rat model. The abstract reports: Exposure of the cells to SGD also resulted in significant increases in HO‑1 expression and nuclear Nrf2 levels, and the HO‑1 inhibitor ZnPP IX and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBreathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
This animal study examined Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart. The abstract describes Mouse model; reported duration 60 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.
This animal study examined The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death. The abstract describes Animal model; sample size 5; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation during EVLP improved the function of DCD lungs, which may increase the utilization of DCD lungs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
This animal study examined Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HRS was demonstrated to attenuate CPB‑induced myocardial injury, suppress AQP‑1 and AQP‑4 expression following CPB treatment and protect myocardial cells via the PI3K/Akt signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
This animal study examined Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Protective effect of hydrogen (H(2)) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
This animal study examined Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results showed a protective effect of HRS on pressure overload-induced cardiac hypertrophy in rats, which may be associated to a decreasing in JAK-STAT…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
This in vitro or cellular study examined Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.
This in vitro or cellular study examined Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway
This animal study examined Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Overall, hydrogen inhalation reduces myocardial infarct size, improves mitochondrial dysfunction, and modulates the levels of apoptosis-related substances. Importantly, Hydrogen reduces acute myocardial infarction damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases.
This narrative review examined Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases. The abstract describes Published literature review. The abstract reports: In the last two decades, mounting evidence has demonstrated that both endogenously produced and exogenously administered , whether via inhalation or -rich water (HRW),…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application.
This animal study examined Hydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application. The abstract describes Animal model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: It has been demonstrated that molecular hydrogen exerts antioxidant, anti-inflammatory, and antiapoptotic effects, leading to cardioprotective benefits. This is an automated editorial draft based on the abstract and requires source review before publication.
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