[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats].
This animal study examined [Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can reduce myocardial reperfusion injury and improve heart function. The mechanism may be due to associated with the down-regulated expressions of Akt…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read More[Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats].
This animal study examined [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 30 min. The abstract reports: Hydrogen-rich saline may decrease cell apoptosis and attenuate myocardial reperfusion injury through inhibiting endoplasmic reticulum stress. The mechanism may be associated with decreasing the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat.
This animal study examined Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhaling was superior to mild hypothermia for improving neurological outcome and survival in cardiac arrest and resuscitation model of systemic hypertension rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
This animal study examined Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Small amounts of inhaled hydrogen were superior to mild hypothermia in improving cardiac function and neurological outcome in this asphyxial rat model of cardiac…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
This animal study examined Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy. The abstract describes Rat model; reported duration 1 hour. The abstract reports: These results revealed a better protective effect of hydrogen on myocardial ischemic/reperfusion injury in rats by attenuating endoplasmic reticulum stress and down-regulating autophagy compared…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEarly Aerobic Exercise Combined with Hydrogen-Rich Saline as Preconditioning Protects Myocardial Injury Induced by Acute Myocardial Infarction in Rats.
This animal study examined Early Aerobic Exercise Combined with Hydrogen-Rich Saline as Preconditioning Protects Myocardial Injury Induced by Acute Myocardial Infarction in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Lipopolysaccharide-Induced Heart Dysfunction by Restoring Fatty Acid Oxidation in Rats by Mitigating C-Jun N-Terminal Kinase Activation.
This animal study examined Hydrogen-Rich Saline Attenuates Lipopolysaccharide-Induced Heart Dysfunction by Restoring Fatty Acid Oxidation in Rats by Mitigating C-Jun N-Terminal Kinase Activation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Inhibition of JNK by HRS showed beneficial effects on LPS-challenged rats, at least in part, by restoring cardiac FAO. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.
This animal study examined Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The HRS treatment resulted in the significant upregulation of malonyl dialdehyde (MDA) and myeloperoxidase (MPO), whilesuperoxide dismutase (SOD) levels were significantly downregulated, compared with…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.
This animal study examined The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that the neuroprotective effects of hydrogen may be mediated by promoting HO-1 expression and attenuated the oxidative injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model
This uncontrolled human study examined Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent animal studies found that hydrogen inhalation after CA greatly improved neurological outcomes by selectively neutralizing highly reactive oxidants, but the effect of hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model
This animal study examined H 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model. The abstract describes Rat model. The abstract reports: Inhalation of H(2) gas is a favorable strategy to mitigate mortality and functional outcome of post-CA syndrome in a rat model, either alone or…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEfficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post-cardiac arrest care (HYBRID II): a multi-centre, randomised, double-blind, placebo-controlled trial
This registered clinical trial examined Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post-cardiac arrest care (HYBRID II): a multi-centre, randomised, double-blind, placebo-controlled trial. The abstract describes Planned or registered research population; sample size 429; hydrogen delivered as hydrogen inhalation. The abstract reports: The trial was terminated prematurely because of the restrictions imposed on enrolment during the COVID-19 pandemic. Between February 1, 2017, and September 30, 2021,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest
This animal study examined Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest. The abstract describes Rat model. The abstract reports: The results showed that H therapy significantly improved post-resuscitation survival and cardiac function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest
This animal study examined Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Our findings suggest that water electrolysis derived 67% hydrogen gas may be an effective therapeutic approach for improving cognitive outcomes associated with global brain…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury.
This animal study examined Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury. The abstract describes Rat model; sample size 60; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrated that H2 significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
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