Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, 2 Treatment with 2% hydrogen improved the 7-day survival rate and decreased the levels of inflammatory cytokines in septic mouse cortex tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in…
Read ArticleIn C57BL/6 mice, western blotting showed that hydrogen treatment reduced Bax and TNFα levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleThe researchers found that 2% H₂ inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at 5 CpG sites,…
Read ArticleIn contrast, catalase and GPx activities were significantly increased in the TMT-only group and decreased after H₂ gas treatment in serum and brain. These preclinical findings add evidence…
Read ArticleIn rats, these findings indicate that HRS could attenuate the consequences of sepsis induced by cecal ligation and puncture in rats, at least in part, by the inhibition…
Read ArticleIn 184 patients, the numerical rating scale (NRS) pain scores were higher in the hydrogen group (4.08 ± 1.77) than the control group (3.54 ± 1.77) on day…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Rodents and humans are able to take a small amount of hydrogen by drinking hydrogen-rich water, but marked effects are…
Read ArticleThe researchers found that the molecular hydrogen delivered by ad libitum HRW consumption significantly inhibited the METH-induced spatial learning impairment and memory loss evidenced in the Barnes maze…
Read ArticleIn mice, however, treatment with hydrogen water for 30 days prevented age-related declines in cognitive ability seen in SAMP8 as assessed by a water maze test and was…
Read ArticleIn rats, surgery-challenged animals showed significant cognitive impairment evidenced by a decreased percentage of freezing time and an increased number of learning trials on days 1, 3, and…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn 73 participants with MCI, to examine whether consumption of H₂ -water attenuated the shortened lifespan, female DAL101 mice started drinking control or H₂ -water at the age…
Read ArticleIn mice, the introduction of hydrogen-rich saline (group PH) partially rescued spatial memory and learning as it shortened escape latency and increased time and crossing frequency of original…
Read ArticleThe researchers found that H₂ can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels in the mouse…
Read ArticleIn male C57BL/6 mice, analysis of CD4 + CD25 + cells (one-way ANOVA) showed that this subset was significantly decreased in the H₂ -treated group (n = 8)…
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