Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model.

This animal study examined Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Our results demonstrated that TMT exposure alters seizure and spatial recognition memory. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates chronic intermittent hypoxia-induced neurocognitive impairment via inhibiting oxidative stress.

This uncontrolled human study examined Hydrogen ameliorates chronic intermittent hypoxia-induced neurocognitive impairment via inhibiting oxidative stress. The abstract describes Human participants; reported duration 5 weeks. The abstract reports: Our results showed that H treatment improved the CIH-induced spatial learning and memory impairments. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture.

This animal study examined Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings indicate that HRS could attenuate the consequences of sepsis induced by cecal ligation and puncture in rats, at least in part, by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Treatment Improves Postoperative Delirium and Cognitive Dysfunction in Elderly Noncardiac Patients.

This uncontrolled human study examined Hydrogen Gas Treatment Improves Postoperative Delirium and Cognitive Dysfunction in Elderly Noncardiac Patients. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Results: Postoperative delirium occurred in 17 (24%) of 70 patients without hydrogen inhalation and in 10 (12%) of 83 patients after hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases

This animal study examined Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment.

This animal study examined Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: We found that the molecular hydrogen delivered by HRW consumption significantly inhibited the METH-induced spatial learning impairment and memory loss evidenced in the Barnes…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.

This in vitro or cellular study examined Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water; reported duration 30 days. The abstract reports: On the basis of our results, hydrogen water merits further investigation for possible therapeutic/preventative use for age-related cognitive disorders. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.

This animal study examined Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Many studies have found that molecular hydrogen (H2) has significant neuroprotection against acute and chronic neurological injury by regulating inflammation and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

This randomized controlled trial examined Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. The abstract describes Human participants; sample size 73. The abstract reports: H2-water may have a potential for suppressing dementia in an oxidative stress model and in the APOE4 carriers with MCI. This is an automated editorial draft based on the abstract and requires source review before publication.

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FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.

This animal study examined FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Autophagy, a self-cannibalization mechanism, has been demonstrated to be involved in VD progression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen-Rich Saline on Hepatectomy-Induced Postoperative Cognitive Dysfunction in Old Mice.

This animal study examined Effects of Hydrogen-Rich Saline on Hepatectomy-Induced Postoperative Cognitive Dysfunction in Old Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model

This animal study examined Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: Histological examinations showed pyknotic neuronal morphologies and elevated reactive oxygen species (ROS) in the VaD hippocampus, whereas H administration mitigated these alterations. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.

This uncontrolled human study examined Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Sepsis is associated with numerous physiological and biochemical abnormalities that result in a life-threatening condition. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.

This animal study examined Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation. The abstract describes Mouse model. The abstract reports: The protective effect of H on cognitive dysfunction induced by SAE may be achieved by inhibiting tau phosphorylation, which is perhaps related with the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.

This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.

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