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Latest Molecular Hydrogen Articles

35 Articles

Mechanism of hydrogen-rich water alleviating radiation-induced cognitive impairment through PI3K/AKT/Caspase-9 pathway mediating anti-oxidation.

By Aug 9, 2026 0 Comments

In rats, hydrogen-rich water can improve the radiation-induced cognitive impairment in rats induced by ionizing radiation through anti-inflammation, anti-oxidation, and regulation of PI3K/AKT/Caspase-9 pathway, and there is a certain dose-effect relationship. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest.

By H2HUBB Jul 28, 2026 0 Comments

In Neuronal degeneration within hippocampal Cornu Ammonis 1 (CA1) regions was examined by Fluoro-Jade staining ex vivo, both hydrogen gas treatment regimens significantly improved spatial learning function and…

The Hydration Equation: Update on Water Balance and Cognitive Performance.

By H2HUBB Jul 28, 2026 0 Comments

This study examined The Hydration Equation: Update on Water Balance and Cognitive Performance. The abstract reports: Traditionally a 2% or more body water deficit was thought to produce…

Redox Effects of Molecular Hydrogen and Its Therapeutic Efficacy in the Treatment of Neurodegenerative Diseases

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. In animal and human clinical trials, the routes for H₂ administration are mainly categorized into three types: H₂ gas inhalation,…

[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].

By H2HUBB Jul 22, 2026 0 Comments

In mice, compared with sepsis group, neurological function significantly improved and damaged neurons in hippocampal CA1 region significantly reduced. The activities of SOD and CAT markedly increased and…

New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.

By H2HUBB Jul 22, 2026 0 Comments

In mice, the daily administration of HRW also progressively reduced the thermal allodynia induced by PTX injection ( p < 0.001; one-way ANOVA, against vehicle plus vehicle-treated animals;…

The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 11.01.2021. Revised: 10.02.2021. Accepted: 15.02.2021. UDC: 612.466:616.613-002-007.271-07 MECHANISM OF INFLUENCE OF MOLECULAR HYDROGEN

By H2HUBB Jul 22, 2026 0 Comments

These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.

Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage.

By H2HUBB Jul 22, 2026 0 Comments

This publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest.

By H2HUBB Jul 22, 2026 0 Comments

In Neuronal degeneration within hippocampal Cornu Ammonis 1 (CA1) regions was examined by Fluoro-Jade staining ex vivo, both hydrogen gas treatment regimens significantly improved spatial learning function and…

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.

By H2HUBB Jul 22, 2026 0 Comments

These results show that molecular hydrogen given in drinking water reverses many of the sequelae of CCI and suggests that it could be an easily administered, highly effective…

Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, treatment with hydrogen-rich saline, which elevated the levels of molecules associated with brain-derived neurotropic factor (BDNF)-mediated synaptic plasticity, improved cognitive performance in the Morris…

Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In male Wistar rats, the neuronal density 3·3±2·1 cells/mm in CA1 region of the ischemic rats increased to 21·7±2·6 cells/mm after they were treated with hydrogen gas. These…

Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, compared to the radiation treated group, the radiation-HRW treated group showed significantly decreased escape latency (P < 0.05), but increased retention time, swimming distance of original…

Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the study has systematically elucidated the molecular mechanism of HRW against ionizing radiation, which can be mediated by modulating targets, pathways and metabolite levels. These preclinical…

Additive effect of clove essential oil combined with hydrogen inhalation improves psychological harm caused by lipopolysaccharide in mice.

By H2HUBB Jul 22, 2026 0 Comments

In mice, cEO administration and H₂ inhalation alone or in combination positively improved inflammation-induced anxiety, depression, and cognitive memory deficits in the mice. These preclinical findings add evidence…