Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications

This narrative review examined Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications. The abstract describes Published literature review; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen rich water in oral pathology: an update.

This narrative review examined Hydrogen rich water in oral pathology: An update. The abstract describes Published literature review; hydrogen delivered as hydrogen water. The abstract reports: I would like to suggest certain updates to the above review article regarding hydrogen rich water in oral pathology with emphasis on recent studies…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report.

This case report or case series examined Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen may aid refractory oral ulcers in Behçet's and primary Sjögren's syndromes, with clinical and immunologic benefits. This is an automated editorial draft based on the abstract and requires source review before publication.

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Assessment of the effects of hydrogen water on human gingival fibroblast cell culture in patients with chronic periodontitis.

This uncontrolled human study examined Assessment of the effects of hydrogen water on human gingival fibroblast cell culture in patients with chronic periodontitis. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen water was nontoxic, increased the migratory capacity, and showed an antioxidative potential on human fibroblasts obtained from periodontally healthy individuals and patients with…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study.

This uncontrolled human study examined Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study. The abstract describes Human participants; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: The HW group showed greater improvements in probing pocket depth and clinical attachment level than the control group at two, four and eight weeks…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.

This animal study examined Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Drinking HW significantly reduced neointima formation after vein grafting in rats. Drinking HW may have therapeutic value as a novel therapy for intimal hyperplasia…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.

This animal study examined Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents. The abstract describes Mouse model. The abstract reports: We first examined the H2 concentrations in blood and organs after its administration and found that oral intake of HRW rapidly but transiently increased…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.

This animal study examined Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Nissl staining and electron microscopy results indicated that HRW intake had protective effects on the CPF-induced damage of hippocampal neurons and neuronal mitochondria. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral ‘hydrogen water’ induces neuroprotective ghrelin secretion in mice.

This uncontrolled human study examined Oral ‘hydrogen water’ induces neuroprotective ghrelin secretion in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: However, H₂ supplementation does not result in detectable changes in striatal H₂ levels, indicating an indirect effect. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich water on aging periodontal tissues in rats.

This animal study examined Effects of hydrogen-rich water on aging periodontal tissues in rats. The abstract describes Rat model; sample size 12; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial.

This randomized controlled trial examined Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial. The abstract describes Human participants; reported duration 14 days. The abstract reports: However, no significant differences were found between groups ( > 0.05). : Administration of hydrogen-rich jelly for 14 days decreased gingival inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Using oral molecular hydrogen supplements to combat microinflammation in humans: a pilot observational study.

This observational study examined Using oral molecular hydrogen supplements to combat microinflammation in humans: a pilot observational study. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Compared to HRW and CaH, OSHCs demonstrated a prolonged reduction in ORP for 60 minutes in vitro and enabled a regulated release of hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.

This animal study examined Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: HW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study

This randomized controlled trial examined Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Assessments were conducted at baseline (T0) and on Days 1 (T1), 3 (T2), 7 (T3), and 14 (T4) post-treatment.ResultsThe HW group showed significant OM…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model.

This animal study examined Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A growing body of evidence suggests that hydrogen is a novel, selective antioxidant that exerts a protective effect against organ damage. This is an automated editorial draft based on the abstract and requires source review before publication.

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